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Submit ReviewBiological Activity for VKGILS-NH2
VKGILS-NH2 is a reversed amino acid sequence control peptide for SLIGKV-NH2, a protease-activated receptor 2 (PAR2) agonist.
Active Analog also available.
Technical Data for VKGILS-NH2
| M. Wt | 614.79 |
| Formula | C28H54N8O7 |
| Sequence |
VKGILS (Modifications: Ser-6 = C-terminal amide) |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 942413-05-0 |
| PubChem ID | 90488839 |
| InChI Key | IYJUKRSADJIIBX-WAUHAFJUSA-N |
| Smiles | [H]N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for VKGILS-NH2
| Solubility | Soluble to 2 mg/ml in water |
Product Datasheets for VKGILS-NH2
References for VKGILS-NH2
References are publications that support the biological activity of the product.
Tognetto et al (2000) Evidence that PAR-1 and PAR-2 mediate prostanoid-dependent contraction in isolated guinea-pig gallbladder. Br.J.Pharmacol. 131 689 PMID: 11030717
Huang (2007) Protease-activated receptor-1 (PAR1) and PAR2 but not PAR4 mediate relaxations in lower esophageal sphincter. Regul.Pept. 142 37 PMID: 17335921
Lin et al (2008) Protease-activated receptor-2 (PAR-2) is a weak enhancer of mucin secretion by human bronchial epithelial cells in vitro. Int.J.Biochem.Cell Biol. 40 1379 PMID: 18077203
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Keywords: VKGILS-NH2, VKGILS-NH2 supplier, Control, peptide, SLIGKV-NH2, PAR, Receptors, Protease-Activated, proteinase-activated, 3392, Tocris Bioscience
Citations for VKGILS-NH2
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