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Submit ReviewZinc protoporphyrin IX
Discontinued Product
This product has been withdrawn from sale and is superseded by Tin protoporphyrin IX dichloride (Cat. No. 0747)
Description: Heme oxygenase and guanylyl cyclase inhibitor
Chemical Name: 7,12-Diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid, zinc complex
Biological Activity for Zinc protoporphyrin IX
Inhibitor of heme oxygenase, which generates the putative neurotransmitter CO.
Technical Data for Zinc protoporphyrin IX
| M. Wt | 626.03 |
| Formula | C34H32N4O4Zn |
| Storage | Store at RT |
| CAS Number | 15442-64-5 |
| PubChem ID | 455799 |
| InChI Key | FUTVBRXUIKZACV-UHFFFAOYSA-L |
| Smiles | C=CC1=C(/C=C3\N=C(/C=C(N5[Zn]6)/C(C)=C(CCC(O)=O)/C5=C4)C(C=C)=C3C)N6C(/C=C2/C(C)=C(CCC(O)=O)C/4=N2)=C1C |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Zinc protoporphyrin IX
References for Zinc protoporphyrin IX
References are publications that support the biological activity of the product.
Brune and Ullrich (1987) Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase. Mol.Pharmacol. 32 497 PMID: 2890093
Grundemar and Ny (1997) Pitfalls using metalloporphyrins in carbon monoxide research. TiPS 18 193 PMID: 9226997
Luo and Vincen (1994) Metalloporphyrins inhibit nitric oxide-dependent cGMP formation in vivo. Eur.J.Pharmacol. 267 263 PMID: 7522180
Verma et al (1993) Carbon monoxide a putative neural messenger. Science 259 381 PMID: 7678352
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Keywords: Zinc protoporphyrin IX, Zinc protoporphyrin IX supplier, Guanylyl, cyclase, inhibits, inhibitors, heme, oxygenase, Heme, guanylyl, sGC, Cyclase, Cyclases, Oxygenase, Oxidase, Oxygenases, Oxidases, Zinc, protoporphyrinIX, 0746, Tocris Bioscience
1 Citation for Zinc protoporphyrin IX
Citations are publications that use Tocris products. Selected citations for Zinc protoporphyrin IX include:
Duann et al (2019) Data on characterization of metalloporphyrin-mediated HO-1 and DAF induction in rat glomeruli and podocytes. Data Brief 22 279 PMID: 30591946
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