Bcl-2 Family Inhibitors
| Cat. No. | Product Name / Activity |
|---|---|
| 7661 | A 1331852 |
| Potent and selective Bcl-xL inhibitor; antitumor and inducer of apoptosis | |
| 6960 | ABT 199 |
| Selective, high affinity Bcl-2 inhibitor; orally bioavailable | |
| 7680 | ABT 263 |
| High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor | |
| 6835 | ABT 737 |
| Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines | |
| 4676 | ARRY 520 trifluoroacetate |
| Potent and selective kinesin spindle protein (KSP) inhibitor; induces Mcl-1 degradation | |
| 2160 | Bax channel blocker |
| Allosteric inhibitor of Bax channel activation | |
| 6323 | FX 1 |
| Bcl-6 inhibitor; 10-fold more potent than endogenous Bcl-6 corepressors | |
| 4819 | Methylprednisolone |
| Anti-apoptotic; upregulates expression of Bcl-xL after injury | |
| 6539 | Obatoclax mesylate |
| Inhibitor of Bcl-2 family members; antiapoptotic |
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