VHL Targeting Ligands Plus Linkers

Products
文献 (1)

Building Blocks

Cat. No. 产品名称/活性
6880 VH 032 amide-alkylC10-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
7106 VH 032 amide-alkylC2-acid
VHL ligand with alkyl linker and terminal acid for onward chemistry
6852 VH 032 amide-alkylC2-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
7216 VH 032 amide-alkylC3-acid
VHL ligand with alkyl linker and terminal acid for onward chemistry
7073 VH 032 amide-alkylC3-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
6680 VH 032 amide-alkylC4-acid
VHL ligand with alkyl linker and terminal acid for onward chemistry
6465 VH 032 amide-alkylC4-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
7217 VH 032 amide-alkylC5-acid
VHL ligand with alkyl linker and terminal acid for onward chemistry
6985 VH 032 amide-alkylC5-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
7867 VH 032 amide-alkylC5-azide
VHL ligand with alkylC5 linker and terminal azide for onward chemistry
7107 VH 032 amide-alkylC6-acid
VHL ligand with alkyl linker and terminal acid for onward chemistry
6853 VH 032 amide-alkylC6-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
7925 VH 032 amide-alkylC7-acid
VHL ligand with alkyl linker and terminal acid for onward chemistry
7074 VH 032 amide-alkylC7-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
7108 VH 032 amide-alkylC8-acid
VHL ligand with alkyl linker and terminal acid for onward chemistry
6890 VH 032 amide-alkylC8-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
7404 VH 032 amide-alkylC9-acid
VHL ligand with alkyl linker and terminal acid for onward chemistry
7566 VH 032 amide-alkylC9-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
7104 VH 032 amide-PEG1-acid
VHL ligand with PEG linker and terminal acid for onward chemistry
6879 VH 032 amide-PEG1-amine
VHL ligand with PEG linker and terminal amine for onward chemistry
7214 VH 032 amide-PEG2-acid
VHL ligand with PEG linker and terminal acid for onward chemistry
6907 VH 032 amide-PEG2-amine
VHL ligand with PEG linker and terminal amine for onward chemistry
6679 VH 032 amide-PEG3-acid
VHL ligand with PEG linker and terminal acid for onward chemistry
6463 VH 032 amide-PEG3-amine
VHL ligand with PEG linker and terminal amine for onward chemistry
8123 VH 032 amide-PEG3-BCN
Functionalized VHL building block for copper-free click chemistry
7215 VH 032 amide-PEG4-acid
VHL ligand with PEG linker and terminal acid for onward chemistry
6464 VH 032 amide-PEG4-amine
VHL ligand with PEG linker and terminal amine for onward chemistry
7105 VH 032 amide-PEG5-acid
VHL ligand with PEG linker and terminal acid for onward chemistry
7568 VH 032 amide-PEG6-amine
VHL ligand with PEG linker and terminal amine for onward chemistry
6909 VH 032 phenol-alkylC4-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
6910 VH 032 phenol-alkylC6-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
7293 VH 101 phenol-alkylC4-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
7294 VH 101 phenol-alkylC6-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry

Literature for VHL Targeting Ligands Plus Linkers

Tocris offers the following scientific literature for VHL Targeting Ligands Plus Linkers to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Targeted Protein Degradation Poster

Targeted Protein Degradation Poster

Degraders (e.g. PROTACs) are bifunctional small molecules, that harness the Ubiquitin Proteasome System (UPS) to selectively degrade target proteins within cells. They consist of three covalently linked components: an E3 ubiquitin ligase ligand, a linker and a ligand for the target protein of interest. Authored in-house, this poster outlines the generation of a toolbox of building blocks for the development of Degraders. The characteristics and selection of each of these components are discussed. Presented at EFMC 2018, Ljubljana, Slovenia