VHL Targeting Ligands Plus Linkers
Building Blocks |
|
| Cat. No. | 产品名称/活性 |
|---|---|
| 6880 | VH 032 amide-alkylC10-amine |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | |
| 7106 | VH 032 amide-alkylC2-acid |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | |
| 6852 | VH 032 amide-alkylC2-amine |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | |
| 7216 | VH 032 amide-alkylC3-acid |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | |
| 7073 | VH 032 amide-alkylC3-amine |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | |
| 6680 | VH 032 amide-alkylC4-acid |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | |
| 6465 | VH 032 amide-alkylC4-amine |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | |
| 7217 | VH 032 amide-alkylC5-acid |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | |
| 6985 | VH 032 amide-alkylC5-amine |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | |
| 7867 | VH 032 amide-alkylC5-azide |
| VHL ligand with alkylC5 linker and terminal azide for onward chemistry | |
| 7107 | VH 032 amide-alkylC6-acid |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | |
| 6853 | VH 032 amide-alkylC6-amine |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | |
| 7925 | VH 032 amide-alkylC7-acid |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | |
| 7074 | VH 032 amide-alkylC7-amine |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | |
| 7108 | VH 032 amide-alkylC8-acid |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | |
| 6890 | VH 032 amide-alkylC8-amine |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | |
| 7404 | VH 032 amide-alkylC9-acid |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | |
| 7566 | VH 032 amide-alkylC9-amine |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | |
| 7104 | VH 032 amide-PEG1-acid |
| VHL ligand with PEG linker and terminal acid for onward chemistry | |
| 6879 | VH 032 amide-PEG1-amine |
| VHL ligand with PEG linker and terminal amine for onward chemistry | |
| 7214 | VH 032 amide-PEG2-acid |
| VHL ligand with PEG linker and terminal acid for onward chemistry | |
| 6907 | VH 032 amide-PEG2-amine |
| VHL ligand with PEG linker and terminal amine for onward chemistry | |
| 6679 | VH 032 amide-PEG3-acid |
| VHL ligand with PEG linker and terminal acid for onward chemistry | |
| 6463 | VH 032 amide-PEG3-amine |
| VHL ligand with PEG linker and terminal amine for onward chemistry | |
| 8123 | VH 032 amide-PEG3-BCN |
| Functionalized VHL building block for copper-free click chemistry | |
| 7215 | VH 032 amide-PEG4-acid |
| VHL ligand with PEG linker and terminal acid for onward chemistry | |
| 6464 | VH 032 amide-PEG4-amine |
| VHL ligand with PEG linker and terminal amine for onward chemistry | |
| 7105 | VH 032 amide-PEG5-acid |
| VHL ligand with PEG linker and terminal acid for onward chemistry | |
| 7568 | VH 032 amide-PEG6-amine |
| VHL ligand with PEG linker and terminal amine for onward chemistry | |
| 6909 | VH 032 phenol-alkylC4-amine |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | |
| 6910 | VH 032 phenol-alkylC6-amine |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | |
| 7293 | VH 101 phenol-alkylC4-amine |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | |
| 7294 | VH 101 phenol-alkylC6-amine |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | |
Literature for VHL Targeting Ligands Plus Linkers
Tocris offers the following scientific literature for VHL Targeting Ligands Plus Linkers to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Targeted Protein Degradation Poster
Degraders (e.g. PROTACs) are bifunctional small molecules, that harness the Ubiquitin Proteasome System (UPS) to selectively degrade target proteins within cells. They consist of three covalently linked components: an E3 ubiquitin ligase ligand, a linker and a ligand for the target protein of interest. Authored in-house, this poster outlines the generation of a toolbox of building blocks for the development of Degraders. The characteristics and selection of each of these components are discussed. Presented at EFMC 2018, Ljubljana, Slovenia
This poster discusses the generation of a toolbox of building blocks for the development of Degraders.
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