Cereblon Targeting Ligands Plus Linkers
Building Blocks |
|
Cat. No. | Product Name / Activity |
---|---|
7516 | Lenalidomide 4'-alkylC3-azide |
Cereblon ligand with alkyl linker and terminal azide for onward chemistry | |
7517 | Lenalidomide 4'-alkylC5-azide |
Cereblon ligand with alkyl linker and terminal azide for onward chemistry | |
7075 | Lenalidomide 4'-PEG1-amine |
Cereblon ligand with PEG linker and terminal amine for onward chemistry | |
7513 | Lenalidomide 4'-PEG1-azide |
Cereblon ligand with PEG linker and terminal azide for onward chemistry | |
7093 | Lenalidomide 4'-PEG2-amine |
Cereblon ligand with PEG linker and terminal amine for onward chemistry | |
7514 | Lenalidomide 4'-PEG2-azide |
Cereblon ligand with PEG linker and terminal azide for onward chemistry | |
7076 | Lenalidomide 4'-PEG3-amine |
Cereblon ligand with PEG linker and terminal amine for onward chemistry | |
7677 | Lenalidomide 5'-amine |
Cereblon ligand with terminal amine for onward chemistry | |
7472 | Lenalidomide 5'-piperazine |
Cereblon ligand with terminal piperazine for onward chemistry | |
7473 | Lenalidomide 5'-piperazine-4-methylpiperidine |
Cereblon ligand with terminal piperidine for onward chemistry | |
7994 | PAG 3'-fluoro-4'-piperazine |
Functionalized cereblon ligand for PROTAC development | |
7996 | PAG 3'-piperazine |
Functionalized cereblon ligand for PROTAC development | |
7997 | PAG 3'-piperazine-4-methylpiperidine New |
Cereblon ligand with terminal piperidine for onward chemistry | |
7998 | PAG 4'-piperazine |
Functionalized cereblon ligand for PROTAC development | |
7999 | PAG 4'-piperazine-4-methylpiperidine |
Cereblon ligand with terminal piperidine for onward chemistry | |
7732 | Pomalidomide 4'-alkylC10-amine |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry | |
6851 | Pomalidomide 4'-alkylC2-amine |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry | |
7439 | Pomalidomide 4'-alkylC2-azide |
Cereblon ligand with alkyl linker and terminal azide for onward chemistry | |
7096 | Pomalidomide 4'-alkylC3-acid |
Cereblon ligand with alkyl linker and terminal acid for onward chemistry | |
7205 | Pomalidomide 4'-alkylC3-amine |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry | |
7440 | Pomalidomide 4'-alkylC3-azide |
Cereblon ligand with alkyl linker and terminal azide for onward chemistry | |
7209 | Pomalidomide 4'-alkylC4-acid |
Cereblon ligand with alkyl linker and terminal acid for onward chemistry | |
7441 | Pomalidomide 4'-alkylC4-azide |
Cereblon ligand with alkyl linker and terminal azide for onward chemistry | |
6682 | Pomalidomide 4'-alkylC5-acid |
Cereblon ligand with alkyl linker and terminal acid for onward chemistry | |
6716 | Pomalidomide 4'-alkylC5-amine |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry | |
7442 | Pomalidomide 4'-alkylC5-azide |
Cereblon ligand with alkyl linker and terminal azide for onward chemistry | |
7210 | Pomalidomide 4'-alkylC6-acid |
Cereblon ligand with alkyl linker and terminal acid for onward chemistry | |
7923 | Pomalidomide 4'-alkylC6-amine |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry | |
7443 | Pomalidomide 4'-alkylC6-azide |
Cereblon ligand with alkyl linker and terminal azide for onward chemistry | |
7097 | Pomalidomide 4'-alkylC7-acid |
Cereblon ligand with alkyl linker and terminal acid for onward chemistry | |
7208 | Pomalidomide 4'-alkylC7-amine |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry | |
7211 | Pomalidomide 4'-alkylC8-acid |
Cereblon ligand with alkyl linker and terminal acid for onward chemistry | |
6944 | Pomalidomide 4'-alkylC8-amine |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry | |
7094 | Pomalidomide 4'-PEG1-acid |
Cereblon ligand with PEG linker and terminal acid for onward chemistry | |
7203 | Pomalidomide 4'-PEG1-amine |
Cereblon ligand with PEG linker and terminal amine for onward chemistry | |
7434 | Pomalidomide 4'-PEG1-azide |
Cereblon ligand with PEG linker and terminal azide for onward chemistry | |
7212 | Pomalidomide 4'-PEG2-acid |
Cereblon ligand with PEG linker and terminal acid for onward chemistry | |
6637 | Pomalidomide 4'-PEG2-amine |
Cereblon ligand with PEG linker and terminal amine for onward chemistry | |
7307 | Pomalidomide 4'-PEG2-azide |
Cereblon ligand with PEG linker and terminal azide for onward chemistry | |
6681 | Pomalidomide 4'-PEG3-acid |
Cereblon ligand with PEG linker and terminal acid for onward chemistry | |
7204 | Pomalidomide 4'-PEG3-amine |
Cereblon ligand with PEG linker and terminal amine for onward chemistry | |
7435 | Pomalidomide 4'-PEG3-azide |
Cereblon ligand with PEG linker and terminal azide for onward chemistry | |
7213 | Pomalidomide 4'-PEG4-acid |
Cereblon ligand with PEG linker and terminal acid for onward chemistry | |
6963 | Pomalidomide 4'-PEG4-amine |
Cereblon ligand with PEG linker and terminal amine for onward chemistry | |
7436 | Pomalidomide 4'-PEG4-azide |
Cereblon ligand with PEG linker and terminal azide for onward chemistry | |
7095 | Pomalidomide 4'-PEG5-acid |
Cereblon ligand with PEG linker and terminal acid for onward chemistry | |
7924 | Pomalidomide 4'-PEG5-amine |
Cereblon ligand with PEG linker and terminal amine for onward chemistry | |
7437 | Pomalidomide 4'-PEG5-azide |
Cereblon ligand with PEG linker and terminal azide for onward chemistry | |
7470 | Pomalidomide 5'-fluoro-6'-piperazine |
Cereblon ligand with terminal piperazine for onward chemistry | |
7471 | Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine |
Cereblon ligand with terminal piperidine for onward chemistry | |
7468 | Pomalidomide 5'-piperazine |
Cereblon ligand with terminal piperazine for onward chemistry | |
7469 | Pomalidomide 5'-piperazine-4-methylpiperidine |
Cereblon ligand with terminal piperidine for onward chemistry | |
7913 | Pomalidomide 5'-piperidine-acid |
Cereblon ligand with piperidine linker and terminal acid for onward chemistry | |
7329 | Thalidomide 4'-ether-alkylC2-acid |
Cereblon ligand with alkyl linker and terminal acid for onward chemistry | |
6850 | Thalidomide 4'-ether-alkylC2-amine |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry | |
7330 | Thalidomide 4'-ether-alkylC3-acid |
Cereblon ligand with alkyl linker and terminal acid for onward chemistry | |
7521 | Thalidomide 4'-ether-alkylC3-azide |
Cereblon ligand with alkyl linker and terminal azide for onward chemistry | |
7331 | Thalidomide 4'-ether-alkylC4-acid |
Cereblon ligand with alkyl linker and terminal acid for onward chemistry | |
6917 | Thalidomide 4'-ether-alkylC4-amine |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry | |
7332 | Thalidomide 4'-ether-alkylC5-acid |
Cereblon ligand with alkyl linker and terminal acid for onward chemistry | |
7522 | Thalidomide 4'-ether-alkylC5-azide |
Cereblon ligand with alkyl linker and terminal azide for onward chemistry | |
7333 | Thalidomide 4'-ether-alkylC6-acid |
Cereblon ligand with alkyl linker and terminal acid for onward chemistry | |
6627 | Thalidomide 4'-ether-alkylC6-amine |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry | |
7829 | Thalidomide 4'-ether-alkylC6-azide |
Cereblon ligand with alkyl linker and terminal azide for onward chemistry | |
7334 | Thalidomide 4'-ether-alkylC7-acid |
Cereblon ligand with alkyl linker and terminal acid for onward chemistry | |
7335 | Thalidomide 4'-ether-alkylC8-acid |
Cereblon ligand with alkyl linker and terminal acid for onward chemistry | |
7403 | Thalidomide 4'-ether-alkylC8-amine |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry | |
7518 | Thalidomide 4'-ether-PEG1-azide |
Cereblon ligand with PEG linker and terminal azide for onward chemistry | |
6686 | Thalidomide 4'-ether-PEG2-alkyne |
Cereblon ligand with PEG linker and terminal alkyne for onward chemistry | |
7519 | Thalidomide 4'-ether-PEG2-azide |
Cereblon ligand with PEG linker and terminal azide for onward chemistry | |
6950 | Thalidomide 4'-ether-PEG3-amine |
Cereblon ligand with PEG linker and terminal amine for onward chemistry | |
7520 | Thalidomide 4'-ether-PEG3-azide |
Cereblon ligand with PEG linker and terminal azide for onward chemistry | |
6951 | Thalidomide 4'-ether-PEG5-amine |
Cereblon ligand with PEG linker and terminal amine for onward chemistry | |
6913 | Thalidomide 4'-oxyacetamide-alkylC1-PEG3-alkylC3-amine |
Cereblon ligand with alkyl-PEG-alkyl linker and terminal amine for onward chemistry | |
6949 | Thalidomide 4'-oxyacetamide-alkylC2-amine |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry | |
6300 | Thalidomide 4'-oxyacetamide-alkylC4-azide |
Cereblon ligand with alkyl linker and terminal azide for onward chemistry | |
6968 | Thalidomide 4'-oxyacetamide-alkylC6-amine |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry | |
6946 | Thalidomide 4'-oxyacetamide-alkylC8-amine |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry | |
6966 | Thalidomide 4'-oxyacetamide-PEG1-amine |
Cereblon ligand with PEG linker and terminal amine for onward chemistry | |
6967 | Thalidomide 4'-oxyacetamide-PEG2-amine |
Cereblon ligand with PEG linker and terminal amine for onward chemistry | |
6467 | Thalidomide 4'-oxyacetamide-PEG3-amine |
Cereblon ligand with PEG linker and terminal amine for onward chemistry | |
7733 | Thalidomide 5'-amine-alkylC10-amine |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry | |
7988 | Thalidomide 5'-amine-alkylC6-amine |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry | |
7557 | Thalidomide 5'-amine-alkylC8-amine |
Cereblon ligand with alkyl linker and terminal amine for onward chemistry | |
7735 | Thalidomide 5'-amine-PEG1-amine |
Cereblon ligand with PEG linker and terminal amine for onward chemistry | |
7736 | Thalidomide 5'-amine-PEG2-amine |
Cereblon ligand with PEG linker and terminal amine for onward chemistry | |
7737 | Thalidomide 5'-amine-PEG3-amine |
Cereblon ligand with PEG linker and terminal amine for onward chemistry |
Literature for Cereblon Targeting Ligands Plus Linkers
Tocris offers the following scientific literature for Cereblon Targeting Ligands Plus Linkers to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
TPD and Induced Proximity Research Product GuideUpdated
This brochure highlights the tools and services available from Bio-Techne to support your Targeted Protein Degradation and Induced Proximity research, including:
- Active Degraders
- TAG Degradation Platform
- Degrader Building Blocks
- Assays for Protein Degradation
- Induced Proximity Tools
Targeted Protein Degradation Poster
Degraders (e.g. PROTACs) are bifunctional small molecules, that harness the Ubiquitin Proteasome System (UPS) to selectively degrade target proteins within cells. They consist of three covalently linked components: an E3 ubiquitin ligase ligand, a linker and a ligand for the target protein of interest. Authored in-house, this poster outlines the generation of a toolbox of building blocks for the development of Degraders. The characteristics and selection of each of these components are discussed. Presented at EFMC 2018, Ljubljana, Slovenia