4-Chlorophenylguanidine hydrochloride

Pricing Availability   Qty
说明: Urokinase inhibitor
纯度: ≥98% (HPLC)
说明书
引用文献 (1)
评论

生物活性 for 4-Chlorophenylguanidine hydrochloride

4-Chlorophenylguanidine hydrochloride is a potent and specific inhibitor of urokinase. Also a positive allosteric modulator at acid sensing ion channel 3 (ASIC3), which increases its pH sensitivity.

技术数据 for 4-Chlorophenylguanidine hydrochloride

分子量 206.07
公式 C7H8ClN3.HCl
储存 Store at RT
纯度 ≥98% (HPLC)
CAS Number 14279-91-5
PubChem ID 44134626
InChI Key RMFZXBDENVVLSL-UHFFFAOYSA-N
Smiles Cl.NC(=N)NC1=CC=C(Cl)C=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for 4-Chlorophenylguanidine hydrochloride

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 100

制备储备液 for 4-Chlorophenylguanidine hydrochloride

以下数据基于产品分子量 206.07。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 4.85 mL 24.26 mL 48.53 mL
5 mM 0.97 mL 4.85 mL 9.71 mL
10 mM 0.49 mL 2.43 mL 4.85 mL
50 mM 0.1 mL 0.49 mL 0.97 mL

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产品说明书 for 4-Chlorophenylguanidine hydrochloride

分析证书/产品说明书
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参考文献 for 4-Chlorophenylguanidine hydrochloride

参考文献是支持产品生物活性的出版物。

Yang et al (1990) Selective inhibition of urok. by substituted phenylguanidines: quantitative structure-activity relationship analyses. J.Med.Chem. 33 2956 PMID: 2231595

Agharkar & Gonzales (2017) 4-Chlorophenylguanidine is an ASIC3 agonist and positive allosteric modulator. J.Pharmacol.Sci. 133 184 PMID: 28259560


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关键词: 4-Chlorophenylguanidine hydrochloride, 4-Chlorophenylguanidine hydrochloride supplier, Urokinase, inhibitors, inhibits, Proteases, Proteinases, upa, PAM, ASIC, 0442, Tocris Bioscience

1 篇 4-Chlorophenylguanidine hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 4-Chlorophenylguanidine hydrochloride 的部分引用包括:

Agharkar & Gonzales 4-Chlorophenylguanidine is an ASIC3 agonist and positive allosteric modulator. J.Pharmacol.Sci. 133 184 PMID: 28259560


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