主页 / 药理学 / Enzyme-Linked Receptors / Cytokine Receptors / 6877002

6877002

Cat. No. 5602 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： CD40-TRAF6 interaction inhibitor
化学名： 3-[(2,5-Dimethylphenyl)amino]-1-phenyl-2-propen-1-one
纯度： ≥99% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for 6877002

6877002 is a CD40-TRAF6 interaction inhibitor. Suppresses CD40-induced IL-1β and IL-6 expression in macrophages in vitro. Improves insulin sensitivity, reduces adipose tissue inflammation, and ameliorates hepatosteatosis in diet-induced obese mice.

技术数据 for 6877002

分子量 251.32
公式 C17H17NO
储存 Store at +4°C
纯度 ≥99% (HPLC)
CAS Number 433249-94-6
PubChem ID 2291556
InChI Key SARYOFMRLSHZFE-ZHACJKMWSA-N
Smiles CC1=CC=C(C)C(N/C=C/C(C2=CC=CC=C2)=O)=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for 6877002

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 25.13 100
ethanol 25.13 100

制备储备液 for 6877002

以下数据基于产品分子量 251.32。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 3.98 mL 19.89 mL 39.79 mL
5 mM 0.8 mL 3.98 mL 7.96 mL
10 mM 0.4 mL 1.99 mL 3.98 mL
50 mM 0.08 mL 0.4 mL 0.8 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

参考文献 for 6877002

参考文献是支持产品生物活性的出版物。

Chatzigeorgiou et al (2014) Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated Ins resistance. Proc.Natl.Acad.Sci.U.S.A. 111 2686 PMID: 24492375

If you know of a relevant reference for 6877002, please let us know.

按标靶查看相关产品

关键词: 6877002, 6877002 supplier, cd40, traf6, tnfalpha, tnfa, tnfα, superfamily, cytokines, receptors, inhibitors, inhibits, inflammation, obesity, diabetes, insulin, Cytokine, Receptors, 5602, Tocris Bioscience

篇 6877002 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 6877002 的引用文献。 您是否知道使用了 Tocris 6877002 的优秀论文？ 请告知我们.

6877002 的评论

目前没有该产品的评论。 Be the first to review 6877002 and earn rewards!

Have you used 6877002?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review