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说明： High affinity angiotensin-converting enzyme (ACE) ligand
生物活性 for Acein
Acein is a high affinity angiotensin-converting enzyme (ACE) ligand (Kd = 2.79 nM). Exhibits no significant effect on ACE enzymatic activity up to 500 nM concentration. Potentiates NMDA + D-serine-induced dopamine release from striatal slices in vitro and the striatum in vivo.
技术数据 for Acein
| 分子量 | 932.5 |
| 公式 | C43H68N10O13 |
| 序列 | PPTTTKFAA |
| 储存 | Store at -20°C |
| PubChem ID | 122177132 |
| InChI Key | VFPBWEDFCUSZRJ-BRCVGTSGSA-N |
| Smiles | [H]N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Acein
参考文献 for Acein
参考文献是支持产品生物活性的出版物。
Neasta et al (2016) The novel nonapeptide acein targets angiotensin converting enzyme in the brain and induces DA release. Br.J.Pharmacol. 173 1314 PMID: 27027724
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关键词: Acein, Acein supplier, High, affinity, angiotensin, converting, enzymes, ACE, ligands, Angiotensin-Converting, Enzyme, 6006, Tocris Bioscience
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