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Submit ReviewPotent and selective CB1 agonist (Ki = 2.2 nM), in water-soluble emulsion (for details see TocrisolveTM 100). Displays 325-fold selectivity over CB2 receptors and is active in vivo.
ACPA, pure oil dissolved in ethanol and Tocrisolve Control also available.
分子量 | 343.55 |
公式 | C23H37NO |
储存 | Store at +4°C |
CAS Number | 229021-64-1 |
PubChem ID | 5311007 |
InChI Key | GLGAUBPACOBAMV-DOFZRALJSA-N |
Smiles | O=C(NC1CC1)CCC\C=C/C\C=C/C/C=C\C/C=C\CCCCC |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Hillard et al (1999) Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1). J.Pharmacol.Exp.Ther. 289 1427 PMID: 10336536
Pertwee (1999) Pharmacology of cannabinoid receptor ligands. Curr.Med.Chem. 6 635 PMID: 10469884
Patel et al (2001) Cannabinoid CB1 receptor agonists produce cerebellar dysfunction in mice. 2001 Symposium on the Cannabinoids, International
关键词: ACPA (in Tocrisolve 100), ACPA (in Tocrisolve 100) supplier, Potent, selective, CB1, agonists, water-soluble, emulsion, cannabinoids, Receptors, cb1r, Arachidonylcyclopropylamide, 1781, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 ACPA (in Tocrisolve™ 100) 的部分引用包括:
Niu et al (2012) Effects of gonadal hormones on the peripheral cannabinoid receptor 1 (CB1R) system under a myositis condition in rats. Sleep 153 2283 PMID: 22940464
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.