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说明： Amphibian bombesin-like peptide
生物活性 for Alytesin
Alytesin is an amphibian bombesin-like peptide. Stimulates gastric acid secretion, intestinal contraction, rat uterine contraction and hypertension in vivo in the dog. Also modulates thermoregulation following central administration in vivo.
技术数据 for Alytesin
| 分子量 | 1535.78 |
| 公式 | C68H106N22O17S |
| 序列 |
XGRLGTQWAVGHLM (Modifications: X = Glp, Met-14 = C-terminal amide) |
| 储存 | Desiccate at -20°C |
| CAS Number | 31078-12-3 |
| PubChem ID | 25078137 |
| InChI Key | ISGGITPLKHZHOL-TXYKKBLVSA-N |
| Smiles | [H]N1[C@@H](CCC1=O)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Alytesin
参考文献 for Alytesin
参考文献是支持产品生物活性的出版物。
Anastasi (1971) Alytesin and bombesin, two peptide analogs from amphibian skin. Naunyn Schmiedebergs Arch.Pharmacol. 269 135 PMID: 4254272
Broccardo et al (1975) Relative potency of bombesin-like peptides. Br.J.Pharmacol. 55 221 PMID: 1201380
Rivier and Brown (1978) Bombesin, bombesin analogues, and related peptides: effects on thermoregulation. Biochemistry 17 1766 PMID: 656396
关键词: Alytesin, Alytesin supplier, Amphibian, bombesin-like, peptide, GRP-Preferring, Receptors, BB1, BB2, BB3, Gastrin-Releasing, Peptide-Preferring, NMB-Preferring, Neuromedin, B-Preferring, Bombesin, 1893, Tocris Bioscience
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Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.