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Submit ReviewANQ 11125
说明： Selective motilin receptor antagonist
生物活性 for ANQ 11125
ANQ 11125 is a selective motilin receptor antagonist (pKd = 8.24). Exhibits no effect on acetylcholine, substance P or serotonin stimulated intestinal contraction.
技术数据 for ANQ 11125
| 分子量 | 1761.05 |
| 公式 | C86H125N19O21 |
| 序列 | FVFIFTYGELQRLQ |
| 储存 | Store at -20°C |
| CAS Number | 153966-48-4 |
| PubChem ID | 90489005 |
| InChI Key | YQKDYBMNXFOSLF-SDGXXZENSA-N |
| Smiles | [H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for ANQ 11125
参考文献 for ANQ 11125
参考文献是支持产品生物活性的出版物。
Depoortere et al (1995) Antagonistic properties of [Phe3,Leu13]porcine motilin. Eur.J.Pharmacol. 286 241 PMID: 8608785
Peeters et al (1994) The motilin antagonist ANQ-11125 blocks motilide-induced contractions in vitro in the rabbit. Biochem.Biophys.Res.Commun. 198 411 PMID: 8297350
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关键词: ANQ 11125, ANQ 11125 supplier, ANQ11125, Motilin, receptor, antagonists, motilides, Receptors, 5074, Tocris Bioscience
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