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BAY 6035

Cat. No. 6561 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Potent and selective SMYD3 inhibitor
化学名： (2S)-1-(3-Azabicyclo[3.1.0]hex-3-ylcarbonyl)-N-(2-cyclopropylethyl)-2,3,4,5-tetrahydro-2-methyl-4-oxo-1H-1,5-benzodiazepine-7-carboxamide
纯度： ≥98% (HPLC)
说明书
引用文献
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生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for BAY 6035

BAY 6035 is a potent SMYD3 inhibitor (IC50 = 70 nM for inhibition of MEKK2 methylation in cells). Exhibits >100-fold selectivity for SMYD3 over other histone methyltransferases.

许可信息

This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the BAY-6035 probe summary on the SGC website.

化合物库 for BAY 6035

BAY 6035 is also offered as part of the Tocriscreen Epigenetics Library. 了解 Tocris 化合物库的更多信息。

技术数据 for BAY 6035

分子量 396.48
公式 C22H28N4O3
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 2247890-13-5
PubChem ID 137499231
InChI Key CKFRXCBNKKOFGO-IGEOTXOUSA-N
Smiles O=C(NCCC1CC1)C2=CC=C3N([C@H](CC(NC3=C2)=O)C)C(N4CC5CC5C4)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for BAY 6035

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 39.65 100
ethanol 39.65 100

制备储备液 for BAY 6035

以下数据基于产品分子量 396.48。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.52 mL 12.61 mL 25.22 mL
5 mM 0.5 mL 2.52 mL 5.04 mL
10 mM 0.25 mL 1.26 mL 2.52 mL
50 mM 0.05 mL 0.25 mL 0.5 mL

Molarity Calculator

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Dilution Calculator

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参考文献 for BAY 6035

参考文献是支持产品生物活性的出版物。

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关键词: BAY 6035, BAY 6035 supplier, BAY6035, SYMD3, inhibitors, inhibits, histone, lysine, methyltransferase, potent, selective, Other, Lysine, Methyltransferases, 6561, Tocris Bioscience

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