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Benzbromarone

Cat. No. 5420 1 条评论 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： TMEM16A/B calcium-activated chloride channel (CaCC) blocker
化学名： (3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)methanone
纯度： ≥99% (HPLC)
说明书
引用文献
评论 (1)
文献 (1)
通路 (1)
生物活性 技术数据 说明书 参考文献

生物活性 for Benzbromarone

TMEM16A/B calcium-activated chloride channel (CaCC) blocker. Inhibits ATP-induced mucin secretion and metacholine-induced airway smooth muscle contraction in vitro.

技术数据 for Benzbromarone

分子量 424.08
公式 C17H12Br2O3
储存 Store at +4°C
纯度 ≥99% (HPLC)
CAS Number 3562-84-3
PubChem ID 2333
InChI Key WHQCHUCQKNIQEC-UHFFFAOYSA-N
Smiles O=C(C3=CC(Br)=C(O)C(Br)=C3)C2=C(CC)OC1=CC=CC=C12

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for Benzbromarone

参考文献是支持产品生物活性的出版物。

Huang et al (2012) Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. Proc.Natl.Acad.Sci.U.S.A. 109 16354 PMID: 22988107

Gallos et al (2013) Functional expression of the TMEM16 family of calcium-activated chloride channels in airway smooth muscle. Am.J.Physiol.Lung Cell Mol.Physiol. 305 625 PMID: 23997176

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关键词: Benzbromarone, Benzbromarone supplier, Benzbromarone, asthma, TMEM16A, TMEM16B, calcium, activated, chloride, channels, blockers, CACC, Ca2+-Activated, Chloride, Channels, 5420, Tocris Bioscience

篇 Benzbromarone 的引用文献

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Benzbromarone was used against Cav3.1 and Cav3.2 to understand its blocking capacities.
By Anonymous on 02/27/2019
种属： Human

Benzbromarone was used against Cav3.1 and Cav3.2 to understand its blocking capacities in increasing concentrations.

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