主页 / 药理学 / Transporters / Ion Pumps/Transporters / Other Ion Pumps/Transporters / Other Ion Pumps/Transporter Inhibitors / BI 01383298

BI 01383298

Cat. No. 6518 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Potent and selective SLC13A5 (Na+/citrate cotransporter) inhibitor
化学名： 1-[(3,5-Dichlorophenyl)sulfonyl]-N-[(4-fluorophenyl)methyl]-4-piperidinecarboxamide
纯度： ≥98% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for BI 01383298

BI 01383298 is a potent and selective inhibitor of human SLC13A5 (Na+/citrate cotransporter; IC50 = 56 nM in HEK cells overexpressing hSLC13A5 and 24 nM in HepG2 cells with endogenous SLC13A5 expression). Displays >1000-fold selectivity over other family members.

许可信息

This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the BI01383298 probe summary on the SGC website.

化合物库 for BI 01383298

BI 01383298 is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for BI 01383298

分子量 445.34
公式 C19H19Cl2FN2O3S
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 2227549-00-8
PubChem ID 134604213
InChI Key VUOYAALVGSMUHC-UHFFFAOYSA-N
Smiles FC1=CC=C(C=C1)CNC(C2CCN(S(=O)(C3=CC(Cl)=CC(Cl)=C3)=O)CC2)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for BI 01383298

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 22.27 50

制备储备液 for BI 01383298

以下数据基于产品分子量 445.34。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.5 mM 4.49 mL 22.45 mL 44.91 mL
2.5 mM 0.9 mL 4.49 mL 8.98 mL
5 mM 0.45 mL 2.25 mL 4.49 mL
25 mM 0.09 mL 0.45 mL 0.9 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

参考文献 for BI 01383298

参考文献是支持产品生物活性的出版物。

Peters (2017) Flipping a citrate switch on liver cancer cells. J.Biol.Chem. 292 13902 PMID: 28821606

If you know of a relevant reference for BI 01383298, please let us know.

按标靶查看相关产品

按产品操作查看相关产品

查看全部 Other Ion Pumps/Transporter Inhibitors

关键词: BI 01383298, BI 01383298 supplier, BI01383298, SLC13A5, inhibitors, inhibits, sodium, citrate, cotransporter, contransport, NaCT, NACT, INDY, Other, Ion, Pumps/Transporters, 6518, Tocris Bioscience

篇 BI 01383298 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 BI 01383298 的引用文献。 您是否知道使用了 Tocris BI 01383298 的优秀论文？ 请告知我们.

BI 01383298 的评论

目前没有该产品的评论。 Be the first to review BI 01383298 and earn rewards!

Have you used BI 01383298?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review