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Bioymifi

Cat. No. 5372 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

5372 has been discontinued.

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说明： DR5 (TRAIL receptor) agonist; induces apoptosis
化学名： 5-[5-[[(5Z)-3-(4-Bromophenyl)-2-imino-4-oxo-5-thiazolidinylidene]methyl]-2-furanyl]-1H-isoindole-1,3(2H)-dione
纯度： ≥97% (HPLC)
说明书
引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for Bioymifi

Bioymifi is a DR5 (TRAIL receptor) agonist. Directly binds extracellular domain of DR5 (Kd = 1.2 μM) and induces the formation of DR5 aggregates. Induces apoptosis of glioblastoma cells.

技术数据 for Bioymifi

分子量 494.32
公式 C22H12BrN3O4S
储存 Store at +4°C
纯度 ≥97% (HPLC)
CAS Number 1420071-30-2
PubChem ID 70678419
InChI Key ULBOWKXOFOTCMU-NLDKGBHCSA-N
Smiles BrC1=CC=C(N3C(/C(SC3=N)=C/C2=CC=C(C4=CC=C(C(NC5=O)=O)C5=C4)O2)=O)C=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for Bioymifi

参考文献是支持产品生物活性的出版物。

Wang et al (2013) Small-molecule activation of the TRAIL receptor DR5 in human cancer cells. Nat.Chem.Biol. 9 84 PMID: 23292651

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关键词: Bioymifi, Bioymifi supplier, TRAIL, tumor, necrosis, factor-related, apoptosis-inducing, ligand, DR5, TNF, agonists, agonism, Cytokine, Receptors, Apoptosis, Inducers, 5372, Tocris Bioscience

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