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Submit ReviewBRD 7552
说明： PDX1 transcription factor inducer; increases insulin expression
化学名： Methyl [2,3-O-bis(Benzo[1,3]dioxol-5-yl-carbamoyl)]-4-O-(4-ethoxycarbonyl-phenylcarbamoyl)-α-D-glucopyranoside
纯度： ≥98% (HPLC)
生物活性 for BRD 7552
BRD 7552 is a PDX1 transcription factor inducer; up regulates PDX1 expression in both primary human islets and ductal cells. Induces epigenetic changes in the PDX1 promoter consistent with transcriptional activation. Increases insulin expression in PANC-1 cells, primary human islets and human duct-derived cells.
技术数据 for BRD 7552
| 分子量 | 711.63 |
| 公式 | C33H33N3O15 |
| 储存 | Store at -20°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 1137359-47-7 |
| PubChem ID | 23891512 |
| InChI Key | AAOLIMLEFKWKOY-IXMSMLDRSA-N |
| Smiles | OC[C@@H]1[C@@H](OC(NC6=CC=C(C(OCC)=O)C=C6)=O)[C@H](OC(NC4=CC=C(OCO5)C5=C4)=O)[C@@H](OC(NC2=CC(OCO3)=C3C=C2)=O)[C@@H](OC)O1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for BRD 7552
参考文献 for BRD 7552
参考文献是支持产品生物活性的出版物。
Yuan et al (2013) A small-molecule inducer of PDX1 expression identified by high-throughput screening. Chem.Biol. 20 1513 PMID: 24290880
关键词: BRD 7552, BRD 7552 supplier, BRD7552, pancreatic, and, duodenal, homeobox, 1, PDX1, transcription, factor, inducers, epigenetic, insulin, diabetes, Other, Transcription, Factors, 5230, Tocris Bioscience
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