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Bropirimine

Cat. No. 4316 1 条评论 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Immunomodulatory and antitumor compound
化学名： 2-Amino-5-bromo-6-phenyl-4(3H)-pyrimidone
纯度： ≥99% (HPLC)
说明书
引用文献
评论 (1)
文献 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Bropirimine

Bropirimine is a immunomodulatory and antitumor compound. Induces interferon (IFN)-α/β production; augments natural killer (NK) cell activity. Orally active.

技术数据 for Bropirimine

分子量 266.09
公式 C10H8BrN3O
储存 Desiccate at RT
纯度 ≥99% (HPLC)
CAS Number 56741-95-8
PubChem ID 65457
InChI Key CIUUIPMOFZIWIZ-UHFFFAOYSA-N
Smiles O=C1N=C(N)NC(C2=CC=CC=C2)=C1Br

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Bropirimine

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 26.61 100

制备储备液 for Bropirimine

以下数据基于产品分子量 266.09。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 3.76 mL 18.79 mL 37.58 mL
5 mM 0.75 mL 3.76 mL 7.52 mL
10 mM 0.38 mL 1.88 mL 3.76 mL
50 mM 0.08 mL 0.38 mL 0.75 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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参考文献 for Bropirimine

参考文献是支持产品生物活性的出版物。

Fujioka et al (1995) Antitumor effects of oral administration of an IF.-inducing pyrimidinone, Bropirimine, on murine renal-cell carcinoma. Cancer Chemother.Pharmacol. 36 7 PMID: 7536641

Tei et al (2002) In vitro antitumor activity of bropirimine against urinary bladder tumor cells. Anticancer Res. 22 1667 PMID: 12168852

If you know of a relevant reference for Bropirimine, please let us know.

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关键词: Bropirimine, Bropirimine supplier, immunomodulators, immunomodulatory, antitumor, induces, interferons, ifn-a, ifn-alpha, ifn-α, ifn-b, ifn-beta, ifn-β, inducers, IFN, Cytokines, 4316, Tocris Bioscience

篇 Bropirimine 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 Bropirimine 的引用文献。 您是否知道使用了 Tocris Bropirimine 的优秀论文？ 请告知我们.

Bropirimine 的评论

平均评分: 5 (Based on 1 Review.)

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Immuno-therapeutic effect of Bropirimine was studied.
By Anonymous on 12/01/2019
种属： Human

Immuno-therapeutic effect of Bropirimine was studied against other immunomodulatory imide drugs.

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