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Submit ReviewBWX 46
说明： Highly selective NPY Y5 agonist
别名： Bis(31/31'){Cys31,Nva34]NPY(27-36)-NH2}
生物活性 for BWX 46
Potent and highly selective NPY Y5 receptor agonist (Ki values are 0.85, 42, 3015 and 245 nM at Y5, Y1, Y2 and Y4 receptors respectively). Stimulates food intake gradually following intrahypothalamic administration in rats.
技术数据 for BWX 46
| 分子量 | 2597.09 |
| 公式 | C116H186N36O28S2 |
| 序列 |
YINLCTRXRY YINLCTRXRY* (Modifications: X = Nva, Tyr-10 = C-terminal amide, X* = Nva, Tyr-10* = C-terminal amide, Disulfide bridge between 5 - 5*) |
| 储存 | Desiccate at -20°C |
| CAS Number | 172997-92-1 |
| PubChem ID | 16142371 |
| InChI Key | NCCWKDKNIQUYAI-JULUKTQUSA-N |
| Smiles | [H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N[H])CC1=CC=C(O)C=C1)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for BWX 46
参考文献 for BWX 46
参考文献是支持产品生物活性的出版物。
Balasubramaniam et al (2002) Bis(31/31'){Cys31, Nva34]NPY(27-36)-NH2}: a neuropeptide Y (NPY) Y5 receptor selective agonist with a latent stimulatory effect on food intake in rats. Peptides 23 1485 PMID: 12182951
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关键词: BWX 46, BWX 46 supplier, selective, Y5, agonists, Neuropeptide, Y, Receptors, NPY, BWX46, neuropeptides, Bis(31/31')[Cys31,, Nva34]NPY(27-36)-NH2}, 2035, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.