C-Laurdan

Pricing Availability   Qty
说明: Two-photon polarity-sensitive lipid membrane probe. Used for: cell membrane imaging. Application: One and Two-photon microscopy for membrane Polarity
化学名: N-Methyl-N-[6-(1-oxododecyl)-2-naphthalenyl]glycine
纯度: ≥95% (HPLC)
说明书
引用文献 (1)
评论
文献 (1)

生物活性 for C-Laurdan

Key information: C-Laurdan is a polarity-sensitive lipid membrane probe.

Used for: lipid raft imaging and cell membrane imaging.

Application: One and two-photon microscopy for membrane polarity.

Properties and Photophysical Data: C-laurdan carry a carboxylic group which can be partially ionized which contributes to its good water solubility and fast membrane incorporation. Two photon excitation spectra = 780 nm. One photon excitation and emission maxima (λ) are 348 nm and 423 nm, respectively; quantum yield = 0.43; extinction coefficient = 12,200 M-1cm-1.

Optical Data for C-Laurdan

C-Laurdan Dye Spectra
Emission Color Blue
λabs 348 nm
λem 423 nm
Extinction Coefficient (ε) 12200 M-1cm-1
Quantum Yield (φ) 0.43
Application One and Two-photon Microscopy for Membrane Polarity

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Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

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技术数据 for C-Laurdan

分子量 397.56
公式 C25H35NO3
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 959839-06-6
PubChem ID 24966947
InChI Key INSWREUMXDGFSD-UHFFFAOYSA-N
Smiles CCCCCCCCCCCC(C1=CC2=C(C=C(N(CC(O)=O)C)C=C2)C=C1)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for C-Laurdan

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMF 39.76 100
ethanol 3.98 10
DMSO 7.95 20

制备储备液 for C-Laurdan

以下数据基于产品分子量 397.56。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.52 mL 12.58 mL 25.15 mL
5 mM 0.5 mL 2.52 mL 5.03 mL
10 mM 0.25 mL 1.26 mL 2.52 mL
50 mM 0.05 mL 0.25 mL 0.5 mL

Molarity Calculator

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Reconstitution Calculator

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参考文献 for C-Laurdan

参考文献是支持产品生物活性的出版物。

Kim et al (2007) A two-photon fluorescent probe for lipid raft imaging: C-laurdan. Chembiochem 8 553 PMID: 17300111

Barucha-Kraszewska et al (2013) Will C-Laurdan dethrone Laurdan in fluorescent solvent relaxation techniques for lipid membrane studies? Langmuir 29 1174 PMID: 23311388

Mazeres et al (2014) Characterization of M-laurdan, a versatile probe to explore order in lipid membranes. F1000Res. 3 172 PMID: 25485094


If you know of a relevant reference for C-Laurdan, please let us know.

关键词: C-Laurdan, C-Laurdan supplier, fluorescent, probe, imaging, lipid, rafts, membrane, polarity, two-photon, 2-photon, one-photon, 1-photon, Fluorescent, Lipid, Probes, and, Cell, Membrane, Stains, 7273, Tocris Bioscience

1 篇 C-Laurdan 的引用文献

引用文献是使用了 Tocris 产品的出版物。 C-Laurdan 的部分引用包括:

Muriel et al (2021) Shortening of membrane lipid acyl chains compensates for phosphatidylcholine deficiency in choline-auxotroph yeast. EMBO J 40 e107966 PMID: 34520050


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