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Ceramide

Cat. No. 0744 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Ser/Thr protein phosphatase activator
化学名： N-Acetylsphingosine
说明书
引用文献 (1)
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Ceramide

Ceramide is a potent modulator of cell proliferation and differentiation. Activates protein phosphatase-1 (PP1) and -2A (PP2A), as well as ceramide-activated protein phosphatase (CAPP) in vitro.

化合物库 for Ceramide

Ceramide is also offered as part of the Tocriscreen Epigenetics Library and Tocriscreen Stem Cell Library. 了解 Tocris 化合物库的更多信息。

技术数据 for Ceramide

分子量 341.53
公式 C20H39NO3
储存 Desiccate at -20°C
CAS Number 3102-57-6
PubChem ID 5497136
InChI Key BLTCBVOJNNKFKC-QUDYQQOWSA-N
Smiles OC[C@@](NC(C)=O)([H])[C@H](O)/C([H])=C([H])/CCCCCCCCCCCCC

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Ceramide

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
ethanol 34.15 100
DMSO 34.15 100

制备储备液 for Ceramide

以下数据基于产品分子量 341.53。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.93 mL 14.64 mL 29.28 mL
5 mM 0.59 mL 2.93 mL 5.86 mL
10 mM 0.29 mL 1.46 mL 2.93 mL
50 mM 0.06 mL 0.29 mL 0.59 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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产品说明书 for Ceramide

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for Ceramide

参考文献是支持产品生物活性的出版物。

Dobowsky and Hannun (1992) Ceramide stimulates a cytosolic protein phosphatase. J.Biol.Chem. 267 5048 PMID: 1312082

Kim et al (1991) Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor α and γ-IF.. J.Biol.Chem. 266 484 PMID: 1845977

Quintans et al (1994) Ceramide mediates the apoptotic response of WEHI 231 cells to anti-immunoglobulin, corticosteroids and irradiation. Biochem.Biophys.Res.Commun. 202 710 PMID: 8048941

Xie and Johnson (1997) Ceramide selectively decreases tau levels in differentiated PC12 cells through modulation of calpain I. J.Neurochem. 69 1020 PMID: 9282924

If you know of a relevant reference for Ceramide, please let us know.

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关键词: Ceramide, Ceramide supplier, Ser/Thr, protein, phosphatase, activators, Protein, Phosphatases, 0744, Tocris Bioscience

1 篇 Ceramide 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Ceramide 的部分引用包括：

Samokhvalov et al (2015) PPARδ signaling mediates the cytotoxicity of DHA in H9c2 cells. Pharmacol Biochem Behav 232 44105 PMID: 25300478

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