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CID 1375606

Cat. No. 6544 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： GPR27 agonist
化学名： 2,4-Dichloro-N-(phenylcarbamoyl)phenylbenzamide
纯度： ≥98% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for CID 1375606

CID 1375606 is a GPR27 agonist. Promotes recruitment of β-arrestin 2 to chimeric GPR27V2 and wild-type GPR27 in a firefly luciferase complementation assay (pEC50 values are 6.34 and 5.1, respectively).

化合物库 for CID 1375606

CID 1375606 is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for CID 1375606

分子量 385.24
公式 C20H14Cl2N2O2
储存 Store at +4°C
纯度 ≥98% (HPLC)
CAS Number 313493-80-0
PubChem ID 1375606
InChI Key PFHDXBXPRBQVAV-UHFFFAOYSA-N
Smiles ClC1=CC(Cl)=C(C(NC2=CC=C(C(NC3=CC=CC=C3)=O)C=C2)=O)C=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for CID 1375606

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 38.52 100

制备储备液 for CID 1375606

以下数据基于产品分子量 385.24。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.6 mL 12.98 mL 25.96 mL
5 mM 0.52 mL 2.6 mL 5.19 mL
10 mM 0.26 mL 1.3 mL 2.6 mL
50 mM 0.05 mL 0.26 mL 0.52 mL

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参考文献 for CID 1375606

参考文献是支持产品生物活性的出版物。

Dupuis et al (2017) Activation of the orphan G protein-coupled receptor GPR27 by surrogate ligands promotes β-arrestin 2 recruitment. Mol.Pharmacol. 91 595 PMID: 28314853

If you know of a relevant reference for CID 1375606, please let us know.

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关键词: CID 1375606, CID 1375606 supplier, GPR27, agonists, agonism, SREB1, CID11375606, Orphan, 7-TM, Receptors, 6544, Tocris Bioscience

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