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Submit ReviewCID 5951923
说明： Krüppel-like factor 5 (KLF5) inhibitor
化学名： 2-[Methyl(tetrahydro-1,1-dioxido-3-thienyl)amino]-2-oxoethyl (E)-3-(3-nitrophenyl)prop-2-enoate
纯度： ≥97% (HPLC)
生物活性 for CID 5951923
CID 5951923 is an inhibitor of Krüppel-like factor 5 (KLF5) transcription factor (IC50 = 2.3 μM). Selectively active against colon cancer cells in a panel of 60 different cancer cell lines.
技术数据 for CID 5951923
| 分子量 | 382.39 |
| 公式 | C16H18N2O7S |
| 储存 | Store at +4°C |
| 纯度 | ≥97% (HPLC) |
| CAS Number | 749872-43-3 |
| PubChem ID | 5951923 |
| InChI Key | URVRJYLSUVXWBC-AATRIKPKSA-N |
| Smiles | O=C(OCC(N(C)C2CS(CC2)(=O)=O)=O)/C=C/C1=CC([N+]([O-])=O)=CC=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for CID 5951923
参考文献 for CID 5951923
参考文献是支持产品生物活性的出版物。
Bialkowska et al (2011) Identification of small-molecule inhibitors of the colorectal cancer oncogene Krüppel-like factor 5 expression by ultrahigh-throughput screening. Mol.Cancer Ther. 10 2043 PMID: 21885866
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关键词: CID 5951923, CID 5951923 supplier, CID5951923, krueppel, kruppel, krüppel-like, factors, klf5, inhibitors, inhibits, Other, Transcription, Factors, 4446, Tocris Bioscience
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