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Submit ReviewCilostazol
说明： PDE3A inhibitor. Also adenosine uptake inhibitor
化学名： 6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
纯度： ≥99% (HPLC)
生物活性 for Cilostazol
Cilostazol is a potent phosphodiesterase III A (PDE3A) inhibitor (IC50 = 0.2 μM) and inhibitor of adenosine uptake. Has antimitogenic, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo.
化合物库 for Cilostazol
Cilostazol is also offered as part of the Tocriscreen 2.0 Max and Tocriscreen FDA-Approved Drugs. 了解 Tocris 化合物库的更多信息。
技术数据 for Cilostazol
| 分子量 | 369.47 |
| 公式 | C20H27N5O2 |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 73963-72-1 |
| PubChem ID | 2754 |
| InChI Key | RRGUKTPIGVIEKM-UHFFFAOYSA-N |
| Smiles | O=C1CCC2=CC(OCCCCC3=NN=NN3C3CCCCC3)=CC=C2N1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Cilostazol
参考文献 for Cilostazol
参考文献是支持产品生物活性的出版物。
Schror (2002) The pharmacology of cilos. Diabetes Obes.Metab. 4 S14 PMID: 12180353
Shintani et al (1985) General pharmacological properties of cilostazol, a new antithrombotic drug. Part I: effects on the central nervous system. Arzneimittelforschung 35 1157 PMID: 4074429
Shintani et al (1985) General pharmacological properties of cilostazol, a new antithrombotic drug. Part II: effects on the peripheral organs. Arzneimittelforschung 35 1163 PMID: 3000392
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关键词: Cilostazol, Cilostazol supplier, PDE3A, inhibitors, inhibits, adenosines, reuptake, Phosphodiesterases, ENT1, Purine, Transporters, Pyrimidine, Equilibrative, Nucleoside, Monoamine, Neurotransmitter, 1692, Tocris Bioscience
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