主页 / Product Type / 荧光成像 / Fluorescent Probes and Stains / Fluorescent Amyloid β Probes / Congo Red

Congo Red

Cat. No. 5167 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

5167 has been discontinued.

说明： Amyloid fibril binding dye; also a VGlut inhibitor
化学名： 3,3'-[(1,1'-Biphenyl)-4,4'-diyl-bis(2,1-diazenediyl)]bis(4-amino-1-naphthalenesulfonic acid) disodium salt
纯度： ≥98% (HPLC)
说明书
引用文献
评论
文献 (1)
生物活性 技术数据 说明书 参考文献

生物活性 for Congo Red

Congo Red is a VGlut inhibitor; decreases synaptic transmission in the dentate gyrus. Also an amyloid fibril-binding dye; inhibits Fib-beta A neurotoxicity by inhibiting fibril formation or by binding to preformed fibrils. Also inhibits the pancreatic islet cell toxicity of diabetes-associated amylin. Excitation wavelength is 497 nm.

技术数据 for Congo Red

分子量 696.66
公式 C32H22N6Na2O6S2
储存 Store at RT
纯度 ≥98% (HPLC)
CAS Number 573-58-0
PubChem ID 11313
InChI Key IQFVPQOLBLOTPF-UHFFFAOYSA-L
Smiles NC2=C(/N=N/C3=CC=C(C4=CC=C(/N=N/C5=C(N)C(C=CC=C6)=C6C(S(=O)(O[Na])=O)=C5)C=C4)C=C3)C=C(S(=O)(O[Na])=O)C1=CC=CC=C12

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for Congo Red

参考文献是支持产品生物活性的出版物。

Lorenzo et al (1994) Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red. Proc.Natl.Acad.Sci.USA 91 12243 PMID: 7991613

Neale et al (2013) Modulation of hippocampal synaptic transmission by the kynurenine pathway member xanthurenic acid and other VGLUT inhibitors. Neuropsychopharmacology. 38 1060 PMID: 23303071

Neale et al (2013) Effect of VGLUT inhibitors on glutamatergic synaptic transmission in the rodent hippocampus and prefrontal cortex. Neurochem.Int. 73 159 PMID: 24121008

按标靶查看相关产品

关键词: Congo Red, Congo Red supplier, vesicular, glutamate, transporters, VGLUT, dye, amyloid, fibril, binding, inhibitors, inhibits, Alzheimer's, disease, diabetes, direct, red, neuroprotective, Labels, and, Stains, Fluorescent, Amyloid, B, Probes, 5167, Tocris Bioscience

篇 Congo Red 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 Congo Red 的引用文献。

Congo Red 的评论

目前没有该产品的评论。 Be the first to review Congo Red and earn rewards!

Have you used Congo Red?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:

  • Fluorescent Dyes, including dyes for flow cytometry
  • Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
  • Tissue Clearing Kits and Reagents
  • Aptamer-based RNA Imaging Reagents
  • Fluorescent Probes for Imaging Bacteria
  • TSA VividTM Fluorophore Kits
  • TSA Reagents for Enhancing IHC, ICC & FISH Signals