Corticosterone

Pricing Availability   Qty
说明: Endogenous glucocorticoid
化学名: (11β)-11,21-Dihydroxypregn-4-ene-3,20-dione
纯度: ≥99% (HPLC)
说明书
引用文献 (4)
评论 (1)
文献 (1)

生物活性 for Corticosterone

Corticosterone is an endogenous glucocorticoid that acts as an agonist at glucocorticoid and mineralocorticoid receptors.

化合物库 for Corticosterone

Corticosterone is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for Corticosterone

分子量 346.46
公式 C21H30O4
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 50-22-6
PubChem ID 5753
InChI Key OMFXVFTZEKFJBZ-HJTSIMOOSA-N
Smiles [H][C@@]23CCC1=CC(CC[C@@](C)1[C@]([H])2[C@@H](O)C[C@@]4(C)[C@]([H])3CC[C@@H]4[C@@](CO)=O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Corticosterone

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 34.65 100

制备储备液 for Corticosterone

以下数据基于产品分子量 346.46。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.89 mL 14.43 mL 28.86 mL
5 mM 0.58 mL 2.89 mL 5.77 mL
10 mM 0.29 mL 1.44 mL 2.89 mL
50 mM 0.06 mL 0.29 mL 0.58 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

产品说明书 for Corticosterone

分析证书/产品说明书
选择另一批次:

参考文献 for Corticosterone

参考文献是支持产品生物活性的出版物。

Lu et al (2006) International union of pharmacology. LXV. The pharmacology and classification of the nuclear receptor superfamily: glucocorticoid, mineralocorticoid, progesterone, and androgen receptors. Pharmacol.Rev. 58 782 PMID: 17132855


If you know of a relevant reference for Corticosterone, please let us know.

按产品操作查看相关产品

查看全部 Glucocorticoid Receptor Agonists

关键词: Corticosterone, Corticosterone supplier, endogenous, glucocorticoid, receptors, mineralocorticoid, nuclear, steroid, hormone, Glucocorticoid, Receptor, Mineralocorticoid, 3685, Tocris Bioscience

4 篇 Corticosterone 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Corticosterone 的部分引用包括:

Roshanak et al (2019) Golgi localized β1-adrenergic receptors stimulate Golgi PI4P hydrolysis by PLCε to regulate cardiac hypertrophy. Elife 8 PMID: 31433293

Shikatani et al (2012) Inhibition of proliferation, migration and proteolysis contribute to corticosterone-mediated inhibition of angiogenesis. PLoS One 7 e46625 PMID: 23056375

Ahmad et al (2019) Perivascular Adipocytes Store Norepinephrine by Vesicular Transport. Arterioscler Thromb Vasc Biol 39 188 PMID: 30567483

Gang et al (2021) Bag-1 mediates glucocorticoid receptor trafficking to mitochondria after corticosterone stimulation: Potential role in regulating affective resilience. J Neurochem 158 358-372 PMID: 33025573


您是否知道使用了 Tocris Corticosterone 的优秀论文? 请告知我们.

Corticosterone 的评论

平均评分: 5 (Based on 1 Review.)

5 星
100%
4 星
0%
3 星
0%
2 星
0%
1 星
0%

Have you used Corticosterone?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:


works well.
By Anonymous on 03/29/2020
分析类型: In Vitro
种属: Rat
细胞系/组织: rat adrenal medulla chromaffin cells

1 mM

PMID: 30567483
review image

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。


Depression Poster

Depression Poster

Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.