D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt

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说明： Ca²⁺ mobilizing second messenger

引用文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性

D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt is an important second messenger involved in Ca²⁺ mobilization from intracellular stores (EC₅₀ = 0.1 μM). Formed from the enzymatic hydrolysis of phosphatidyl inositol-4,5-bisphosphate.

技术数据

分子量	648.64
公式	C₆H₉O₁₅P₃.K₆
储存	Store at -20°C
CAS Number	103476-24-0
PubChem ID	16219525
InChI Key	DVOPWCOAGWTTEN-PPKFVSOLSA-H
Smiles	[K+].[K+].[K+].[K+].[K+].[K+].O[C@@H]1[C@H](O)[C@@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@@H](O)[C@@H]1OP([O-])([O-])=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据

溶解性	Soluble in water

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分析证书/产品说明书

化学品安全技术说明书

参考文献

参考文献是支持产品生物活性的出版物。

Joseph et al (1984) myo-Inositol 1,4,5-trisphosphate. J.Biol.Chem. 259 3077 PMID: 6607924

Murphy et al (1996) Enantiomers of myo-inositol-1,3,4-trisphosphate and myo-inositol-1,4,6-trisphosphate: stereospecific recognition by cerebellar and platelet myo-inositol-1,4,5-trisphosphate receptors. Mol.Pharmacol. 50 1223 PMID: 8913354

Wilcox et al (1998) New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptor. TiPS 19 467 PMID: 9850611

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Li et al (2016) Junctophilin 3 expresses in pancreatic beta cells and is required for glucose-stimulated Ins secretion. Cell Death Dis 7 e2275 PMID: 27336719

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