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Submit Review[D-Phe12]-Bombesin
说明： Bombesin receptor antagonist
生物活性 for [D-Phe12]-Bombesin
Bombesin receptor antagonist; inhibits bombesin-induced amylase release in guinea pig pancreas (IC50 = 4 mM). Centrally active in vivo.
技术数据 for [D-Phe12]-Bombesin
| 分子量 | 1629.9 |
| 公式 | C74H112N22O18S |
| 序列 |
XQRLGNQWAVGFLM (Modifications: X = Glp, Phe-12 = D-Phe, Gly-14 = C-terminal amide) |
| 储存 | Desiccate at -20°C |
| CAS Number | 108437-87-2 |
| PubChem ID | 57340149 |
| InChI Key | NXZVGUQLNAVPLJ-VKXSZNMLSA-N |
| Smiles | [H]N1[C@@H](CCC1=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for [D-Phe12]-Bombesin
参考文献 for [D-Phe12]-Bombesin
参考文献是支持产品生物活性的出版物。
Heinz-Erian et al (1987) [D-Phe12]Bombesin analogues: a new class of bombesin receptor antagonists. Am.J.Physiol. 252 G439 PMID: 2435173
Merali et al (1988) (D-Phe12) Bombesin and substance P analogues function as central bombesin receptor antagonists. Synapse 2 282 PMID: 2463692
Moody et al (1988) Localization of receptors for bombesin-like peptides in the rat brain. Ann.N.Y.Acad.Sci. 547 114 PMID: 2853589
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关键词: [D-Phe12]-Bombesin, [D-Phe12]-Bombesin supplier, Bombesin, receptor, antagonists, GRP-Preferring, Receptors, BB1-3, Gastrin-Releasing, Peptide-Preferring, NMB-Preferring, Neuromedin, B-Preferring, 1913, Tocris Bioscience
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