DFHO

Cat. No. 6434 1 次引用提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： RFP fluorophore mimic for imaging RNA in living cells; activated by binding Corn aptamers

化学名： 4-(3,5-Difluoro-4-hydroxybenzylidene)-1-methyl-5-oxo-4,5-dihydro-1H-imidazole-2-carbaldehyde oxime

纯度： ≥98% (HPLC)

说明书

引用文献 (1)

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for DFHO

DFHO is a mimic of red fluorescent protein (RFP) fluorophore for imaging RNA in living cells. DFHO fluorescence is activated by binding to Corn aptamer (K_d = 70 nM) or Squash aptamer (K_d = 54 nM). Excitation/emission maxima (λ) = 505/545 nm; extinction coefficient = 29000 M^-1 cm^-1.

技术数据 for DFHO

分子量	281.22
公式	C₁₂H₉F₂N₃O₃
储存	Store at -20°C
纯度	≥98% (HPLC)
CAS Number	1420815-34-4
Smiles	CN1C(/C=N/O)=N/C(C1=O)=C\C2=CC(F)=C(C(F)=C2)O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for DFHO

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	DMSO	28.12	100

制备储备液 for DFHO

以下数据基于产品分子量 281.22。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	3.56 mL	17.78 mL	35.56 mL
5 mM	0.71 mL	3.56 mL	7.11 mL
10 mM	0.36 mL	1.78 mL	3.56 mL
50 mM	0.07 mL	0.36 mL	0.71 mL

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产品说明书 for DFHO

分析证书/产品说明书

化学品安全技术说明书

参考文献 for DFHO

参考文献是支持产品生物活性的出版物。

Song et al (2017) Imaging RNA polymerase III transcription using a photostable RNA-fluorophore complex. Nat.Chem.Biol. 13 1187 PMID: 28945233

Warner et al (2017) A homodimer interface without base pairs in an RNA mimic of red fluorescent protein. Nat.Chem.Biol. 13 1195 PMID: 28945234

Dey et al (2022) Repurposing an adenine riboswitch into a fluorogenic imaging and sensing tag. Nat.Chem.Biol. 18 180 PMID: 34937909

Truong et al (2022) The fluorescent aptamer Squash extensively repurposes the adenine riboswitch fold. Nat.Chem.Biol. 18 191 PMID: 34937911

If you know of a relevant reference for DFHO, please let us know.

按标靶查看相关产品

关键词: DFHO, DFHO supplier, fluorescent, RNA, imaging, fluorophore, red, protein, Corn, aptamer, light, up, aptamers, FLAPs, Aptamer-based, Imaging, Fluorescent, Probes, 6434, Tocris Bioscience

1 篇 DFHO 的引用文献

引用文献是使用了 Tocris 产品的出版物。 DFHO 的部分引用包括：

Aaron E et al (2023) Trumpet is an operating system for simple and robust cell-free biocomputing. Nat Commun 14 2257 PMID: 37080970

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该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Fluorescent Dyes and Probes Research Product Guide

This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:

Fluorescent Dyes, including dyes for flow cytometry
Fluorescent Probes and Stains, including our new MitoBrilliant^TM mitochondria stains
Tissue Clearing Kits and Reagents
Aptamer-based RNA Imaging Reagents
Fluorescent Probes for Imaging Bacteria
TSA Vivid^TM Fluorophore Kits
TSA Reagents for Enhancing IHC, ICC & FISH Signals