Dynamin inhibitory peptide, myristoylated

Name: Dynamin inhibitory peptide, myristoylated
Brand: Tocris Bioscience
SKU: 1775

Cat. No. 1775 4 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1775 has been discontinued.

View all Dynamin products.

说明： Cell-permeable dynamin inhibitor

纯度： ≥95% (HPLC)

说明书

引用文献 (4)

生物活性技术数据说明书参考文献

生物活性

Dynamin inhibitory peptide, myristoylated is a cell-permeable version of dynamin inhibitory peptide, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Reduces NMDA receptor internalization.

Control Peptide also available.

技术数据

分子量	1330.64
公式	C₆₁H₁₀₇N₁₉O₁₄
序列	QVPSRPNRAP (Modifications: Gln-1 = Myr-Gln, Pro-10 = C-terminal amide)
储存	Store at -20°C
纯度	≥95% (HPLC)
CAS Number	251634-22-7
PubChem ID	90471171
InChI Key	IFTSFTVOMZTNME-ZUSDHBTASA-N
Smiles	[H]N([C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(N)=O)C(=O)CCCCCCCCCCCCC

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书

分析证书/产品说明书

化学品安全技术说明书

参考文献

参考文献是支持产品生物活性的出版物。

Grabs et al (1997) The SH3 domain of amphiphysin binds the proline-rich domain of dynamin at a single site that defines a new SH3 binding consensus sequence. J.Biol.Chem. 272 13419 PMID: 9148966

Kittler et al (2000) Constitutive endocytosis of GABA_A receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. J.Neurosci. 20 7972 PMID: 11050117

Nong et al (2003) Glycine binding primes NMDA receptor internalization. Nature 422 302 PMID: 12646920

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关键词: Dynamin inhibitory peptide, myristoylated, Dynamin inhibitory peptide, myristoylated supplier, Cell-permeable, dynamin, inhibitors, inhibits, Dynamin, Epac, GTPases, Mitosis, 1775, Tocris Bioscience