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Submit Review3196 has been discontinued.
Dynorphin B is an opioid peptide that is the preferred endogenous agonist for the kappa opioid receptor. Displays moderate selectivity for κ1b.
分子量 | 1570.85 |
公式 | C74H115N21O17 |
序列 | YGGFLRRQFKVVT |
储存 | Store at -20°C |
纯度 | ≥95% (HPLC) |
CAS Number | 83335-41-5 |
PubChem ID | 25075991 |
InChI Key | AGTSSZRZBSNTGQ-ITZCFHCWSA-N |
Smiles | [H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Dhawan et al (1996) International union of pharmacology. XII. Classification of opioid receptors. Pharmacol.Rev. 48 567 PMID: 8981566
Pasternak et al (1999) Antisense mapping KOR-1: evidence for multiple kappa analgesic mechanisms. Brain Res. 826 289 PMID: 10224306
Tan-No et al (2008) Cysteine protease inhibitors suppress the development of tolerance to mor. antinociception. Neuropeptides 42 239 PMID: 18440066
关键词: Dynorphin B, Dynorphin B supplier, Endogenous, κ-opioid, kappa-opioid, agonists, KOP, Receptors, OP2, DynorphinB, Kappa, Opioid, 3196, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 Dynorphin B 的部分引用包括:
Pedersen et al (2021) A novel luminescence-based-β-arrestin recruitment assay for unmodified receptors. J Biol Chem PMID: 33684444
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.
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