Eptifibatide

Discontinued Product

4725 has been discontinued.

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说明: Glycoprotein IIb/IIIa inhibitor; inhibits platelet aggregation
纯度: ≥95% (HPLC)
说明书
引用文献
评论
文献 (2)

生物活性 for Eptifibatide

Eptifibatide is a glycoprotein (GP) IIb/IIIa inhibitor. Reversibly and competitively binds to GPIIa/IIIb on platelets, inhibiting aggregation.

技术数据 for Eptifibatide

分子量 832.5
公式 C35H49N11O9S2
序列 XXGDWPC

(Modifications: X1 = Mpa, X2 = Har, Disulfide bridge: 1-7, Cys-7 = C-terminal amide)

储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 188627-80-7
PubChem ID 448812
InChI Key CZKPOZZJODAYPZ-LROMGURASA-N
Smiles NC(=N)NCCCC[C@@H]1NC(=O)CCSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc3ccccc23)NC(=O)[C@H](CC(O)=O)NC(=O)CNC1=O)C(N)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Eptifibatide

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参考文献 for Eptifibatide

参考文献是支持产品生物活性的出版物。

O'Shea and Tcheng (2002) Eptifibatide: a potent inhibitor of the platelet receptor integrin glycoprotein IIb/IIIa. Expert Opin.Pharmacother. 3 1199 PMID: 12150697

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关键词: Eptifibatide, Eptifibatide supplier, Glycoprotein, GP, IIb/IIIa, inhibitors, inhibits, platelets, aggregation, antiplatelet, Integrins, Cell, Adhesion, Molecules, 4725, Tocris Bioscience

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*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。


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The Tocris chemistry team has considerable chemistry knowledge and skill which it has recently been applying to the generation of new chemical probes from known tools and compounds to help answer biological questions. This poster presents some of the work carried out by Tocris scientists and focuses on two areas: the generation of libraries of chemical building blocks to support Degrader (PROTAC) research and the development of a fluorescent probe to study integrin biology. Presented at Chemical Tools for Complex Biological Systems II, 2019, Janelia Research Campus, USA.