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Submit ReviewEptifibatide is a glycoprotein (GP) IIb/IIIa inhibitor. Reversibly and competitively binds to GPIIa/IIIb on platelets, inhibiting aggregation.
分子量 | 832.5 |
公式 | C35H49N11O9S2 |
序列 |
XXGDWPC (Modifications: X1 = Mpa, X2 = Har, Disulfide bridge: 1-7, Cys-7 = C-terminal amide) |
储存 | Store at -20°C |
纯度 | ≥95% (HPLC) |
CAS Number | 188627-80-7 |
PubChem ID | 448812 |
InChI Key | CZKPOZZJODAYPZ-LROMGURASA-N |
Smiles | NC(=N)NCCCC[C@@H]1NC(=O)CCSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc3ccccc23)NC(=O)[C@H](CC(O)=O)NC(=O)CNC1=O)C(N)=O |
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参考文献是支持产品生物活性的出版物。
O'Shea and Tcheng (2002) Eptifibatide: a potent inhibitor of the platelet receptor integrin glycoprotein IIb/IIIa. Expert Opin.Pharmacother. 3 1199 PMID: 12150697
关键词: Eptifibatide, Eptifibatide supplier, Glycoprotein, GP, IIb/IIIa, inhibitors, inhibits, platelets, aggregation, antiplatelet, Integrins, Cell, Adhesion, Molecules, 4725, Tocris Bioscience
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