FFN 200 dihydrochloride

Pricing Availability   Qty
说明: Selective fluorescent VMAT2 substrate
化学名: 4-(2-Aminoethyl)-7-amino-2H-1-benzopyran-2-one dihydrochloride
纯度: ≥98% (HPLC)
说明书
引用文献 (1)
评论
文献 (1)

生物活性 for FFN 200 dihydrochloride

FFN 200 dihydrochloride is a selective fluorescent VMAT2 substrate. Selectively traces exocytosis in dopaminergic neuronal cell culture and brain tissue. Excitation and emission maxima are 352 and 451 nm, respectively.

许可信息

Sold with the permission of Columbia University.

Applications in Cultured Dopamine Neurons for FFN 200 dihydrochloride

FFN200 in vesicle clusters in axons of cultured dopaminergic neurons, and exocytosis upon high potassium stimulation (time lapse acquisition at 12 images/min).

技术数据 for FFN 200 dihydrochloride

分子量 277.15
公式 C11H12N2O2.2HCl
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 2080306-27-8
PubChem ID 124201850
InChI Key YNQXRSNAOWBGLD-UHFFFAOYSA-N
Smiles NC1=CC(OC(C=C2CCN)=O)=C2C=C1.Cl.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for FFN 200 dihydrochloride

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 27.71 100
DMSO 27.71 100

制备储备液 for FFN 200 dihydrochloride

以下数据基于产品分子量 277.15。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 3.61 mL 18.04 mL 36.08 mL
5 mM 0.72 mL 3.61 mL 7.22 mL
10 mM 0.36 mL 1.8 mL 3.61 mL
50 mM 0.07 mL 0.36 mL 0.72 mL

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产品说明书 for FFN 200 dihydrochloride

参考文献 for FFN 200 dihydrochloride

参考文献是支持产品生物活性的出版物。

Pereira et al (2015) Fluorescent false neurotransmitter reveals functionally silent DA vesicle clusters in the striatum. Nat.Neurosci. 19 578 PMID: 26900925

Li (2017) Probes for monitoring regulated exocytosis. Cell Calcium 64 65 PMID: 28089267


If you know of a relevant reference for FFN 200 dihydrochloride, please let us know.

关键词: FFN 200 dihydrochloride, FFN 200 dihydrochloride supplier, FFN200, dihydrochloride, fluorescent, false, neurotransmitters, VMAT2, vesicular, monoamine, transporters, 2, dopaminergic, substrates, Fluorescent, Substrates, Vesicular, Monoamine, Transporters, Transporter, Probes, 5911, Tocris Bioscience

1 篇 FFN 200 dihydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 FFN 200 dihydrochloride 的部分引用包括:

Matthias et al (2022) Endogenously produced catecholamines improve the regulatory function of TLR9-activated B cells. PLoS Biol 20 e3001513 PMID: 35073310


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