FFN 206 dihydrochloride

Cat. No. 5043 2 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Pricing	Availability		Qty

说明： Fluorescent VMAT2 substrate

化学名： 4-(2-Aminoethyl)-7-(methylamino)-2H-1-benzopyran-2-one dihydrochloride

纯度： ≥99% (HPLC)

引用文献 (2)

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for FFN 206 dihydrochloride

FFN 206 dihydrochloride is a fluorescent VMAT2 substrate (IC₅₀ app = 1.15 μM). Allows detection of VMAT2 subcellular locations in cell culture. Exhibits no detectable inhibition of DAT. Excitation maximum = 369 nm; emission maximum = 464 nm.

许可信息

Sold with the permission of Columbia University

Optical Data for FFN 206 dihydrochloride

Emission Color	Blue
λ_abs	369 nm
λ_em	464 nm
Application	Fluorescence Microscopy, Confocal Microscopy

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技术数据 for FFN 206 dihydrochloride

分子量	291.17
公式	C₁₂H₁₄N₂O₂.2HCl
储存	Store at -20°C
纯度	≥99% (HPLC)
CAS Number	1883548-88-6
PubChem ID	91826079
InChI Key	ODENAPXTSFPACZ-UHFFFAOYSA-N
Smiles	CNC1=CC=C2C(OC(C=C2CCN)=O)=C1.Cl.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for FFN 206 dihydrochloride

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
	water	29.12	100
	DMSO	14.56	50

制备储备液 for FFN 206 dihydrochloride

以下数据基于产品分子量 291.17。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	3.43 mL	17.17 mL	34.34 mL
5 mM	0.69 mL	3.43 mL	6.87 mL
10 mM	0.34 mL	1.72 mL	3.43 mL
50 mM	0.07 mL	0.34 mL	0.69 mL

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产品说明书 for FFN 206 dihydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for FFN 206 dihydrochloride

参考文献是支持产品生物活性的出版物。

Hu et al (2013) New fluorescent substrate enables quantitative and high-throughput examination of vesicular monoamine transporter 2 (VMAT2). ACS Chem.Biol. 8 1947 PMID: 23859623

If you know of a relevant reference for FFN 206 dihydrochloride, please let us know.

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2 篇 FFN 206 dihydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 FFN 206 dihydrochloride 的部分引用包括：

Simon C et al (2019) Drosophila Ptp4E regulates vesicular packaging for monoamine-neuropeptide co-transmission. J Cell Sci 132 PMID: 30837287

Hoffman et al (2018) Merkel cells activate sensory neural pathways through adrenergic synapses. Neuron 100 1401 PMID: 30415995

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