FFN 270

Cat. No. 6717 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Fluorescent substrate for NET and VMAT2

化学名： 3-(2-Aminoethyl)-8-fluoro-7-hydroxy-2H-chromen-2-one hydrochloride

纯度： ≥98% (HPLC)

说明书

引用文献

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for FFN 270

FFN 270 is a fluorescent false neurotransmitter (FFN). Fluorescent substrate for NET and VMAT2. Labels noradrenergic neurons and their synaptic vesicles, and enables imaging of synaptic vesicle content release from specific axonal sites in vivo. Selectively labels NA neurons over other monoamine and CNS targets. Exhibits two resolved absorption/excitation maxima depending on solvent pH (excitation maxima: 320 nm or 365 nm, emission maxima: 475 nm).

许可信息

Sold with the permission of Columbia University.

Amphetamine-stimulated release of FFN 270 from noradrenergic projections for FFN 270

Amphetamine releases FFN 270 from noradrenergic projections in vivo. The video shows FFN 270 puncta in Layer 1 of the barrel cortex in mice taken before and after injection of amphetamine (AMPH).

技术数据 for FFN 270

分子量	259.66
公式	C₁₁H₁₀FNO₃.HCl
储存	Store at -20°C
纯度	≥98% (HPLC)
CAS Number	2341841-05-0
Smiles	OC1=CC=C2C(OC(C(CCN)=C2)=O)=C1F.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for FFN 270

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	DMSO	25.97	100

制备储备液 for FFN 270

以下数据基于产品分子量 259.66。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	3.85 mL	19.26 mL	38.51 mL
5 mM	0.77 mL	3.85 mL	7.7 mL
10 mM	0.39 mL	1.93 mL	3.85 mL
50 mM	0.08 mL	0.39 mL	0.77 mL

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产品说明书 for FFN 270

分析证书/产品说明书

化学品安全技术说明书

参考文献 for FFN 270

参考文献是支持产品生物活性的出版物。

Dunn et al (2018) Designing a norepinephrine optical tracer for imaging individual noradrenergic synapses and their activity in vivo. Nat.Commun. 9 2838 PMID: 30026491

If you know of a relevant reference for FFN 270, please let us know.

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关键词: FFN 270, FFN 270 supplier, FFN270, fluorescent, false, neurotransmitter, FFN, inhibitors, inhibits, neuronal, vesicular, monoamine, transporters, VMAT2, noradrenalin, noradrenaline, NET, adrenergic, norepinephrine, tracer, Fluorescent, Substrates, Vesicular, Monoamine, Transporters, Adrenergic, Transporter, Probes, 6717, Tocris Bioscience

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Fluorescent Dyes and Probes Research Product Guide

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