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Submit ReviewFFN 511 is a fluorescent false neurotransmitter (FFN). Targets neuronal vesicular monoamine transporter (VMAT) 2; inhibits serotonin binding to VMAT2 (IC50 = 1 μM). Excitation and emission maxima are 406 and 501 nm in pH 7 buffer, respectively.
Sold with the permission of Columbia University
分子量 | 284.35 |
公式 | C17H20N2O2 |
储存 | Store at +4°C |
纯度 | ≥99% (HPLC) |
CAS Number | 1004548-96-2 |
PubChem ID | 23725121 |
InChI Key | SKTIZSRPCXRDHX-UHFFFAOYSA-N |
Smiles | NCCC(C1=C(O4)C3=C2C(CCCN2CCC3)=C1)=CC4=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Gubernator et al (2009) Fluorescent false neurotransmitters visualize DA release from individual presynaptic terminals. Science 324 1441 PMID: 19423778
Zhang et al (2009) DA release at individual presynaptic terminals visualized with FFNs. J.Vis.Exp. 30 PMID: 19721412
关键词: FFN 511, FFN 511 supplier, FFN511, fluorescent, false, neurotransmitter, inhibitors, inhibits, neuronal, vesicular, monoamine, transporters, serotonin, 5HT, binding, Noradrenalin, noradrenaline, NET, Adrenergic, Transporters, Monoamine, Neurotransmitter, DAT, Dopamine, Serotonin, SERT, 5-HT, reuptake, 5-Hyd, Fluorescent, Substrates, Vesicular, Transporter, Probes, 3878, Tocris Bioscience
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