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View all Voltage-gated Sodium (Na<sub>V</sub>) Channels products.Dual Na+/Ca2+ channel blocker; a cerebral and peripheral vasodilator. Neuroprotective.
分子量 | 477.42 |
公式 | C26H26F2N2.2HCl |
储存 | Desiccate at RT |
CAS Number | 30484-77-6 |
PubChem ID | 5282407 |
InChI Key | RXKMOPXNWTYEHI-RDRKJGRWSA-N |
Smiles | Cl[H].Cl[H].FC1=CC=C(C=C1)C(N1CCN(C\C=C\C2=CC=CC=C2)CC1)C1=CC=C(F)C=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Eichler et al (1994) The ability of diphenylpiperazines to prevent neuronal death in dorsal root ganglion neurons in vitro after axotomy. J.Neurochem. 62 2148 PMID: 8189223
Pauwels et al (1991) Ca+ and Na+ channels involved in neuronal cell death - protection by flunar. Life.Sci. 48 1881 PMID: 1850815
Urenjak and Obrenovitch (1996) Pharmacological modulation of voltage gated Na+ channels: a rational and effective strategy against ischemic brain damage. Pharmacol.Rev. 48 21 PMID: 8685246
关键词: Flunarizine dihydrochloride, Flunarizine dihydrochloride supplier, Dual, Na+/Ca2+, channel, T-type, blockers, Sodium, NaV, Channels, voltage-gated, voltage-dependent, Na+, Calcium, CaV, Ca2+, Voltage-gated, Cav3.x, 0522, Tocris Bioscience
平均评分: 4 (Based on 1 Review.)
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To alter neuronal activity in vitro.