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说明： Ubiquitin isopeptidase inhibitor; induces apoptosis
化学名： Tetrahydro-3,5-bis[(4-nitrophenyl)methylene]-4H-thiopyran-4-one-1,1-dioxide
纯度： ≥98% (HPLC)
生物活性 for G5
G5 is an ubiquitin isopeptidase inhibitor; activates caspases and apoptosis in an apoptosome-independent pathway.
技术数据 for G5
| 分子量 | 414.39 |
| 公式 | C19H14N2O7S |
| 储存 | Store at -20°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 108477-18-5 |
| PubChem ID | 5918438 |
| InChI Key | SSAMIOWVUGBIJK-KAVGSWPWSA-N |
| Smiles | O=C1/C(CS(=O)(C/C1=C\C2=CC=C([N+]([O-])=O)C=C2)=O)=C/C3=CC=C([N+]([O-])=O)C=C3 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for G5
参考文献 for G5
参考文献是支持产品生物活性的出版物。
Hafner-Bratkovic et al (2018) NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway. Nat.Commun. 9 5182 PMID: 30518920
Foti et al (2009) Characterization of caspase-dependent and caspase-independent deaths in glioblastoma cells treated with inhibitors of the ubiquitin-proteasome system. Mol.Cancer Ther. 8 3140 PMID: 19887551
Aleo et al (2006) Identification of new compounds that trigger apoptosome-independent caspase activation and apoptosis. Cancer Res. 66 9235 PMID: 16982768
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关键词: G5, G5 supplier, Ubiquitin, isopeptidases, inhibitors, inhibits, caspases, activators, apoptosis, inducers, Deubiquitinating, Enzymes, Apoptosis, Inducers, 6776, Tocris Bioscience
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