Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewGSK J5
Discontinued Product
This product has been withdrawn from sale and is superseded by GSK J5 HCl (Cat. No. 6935)
说明： Inactive isomer of GSK J4 (Cat. No. 4594); cell permeable
化学名： N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester
纯度： ≥98% (HPLC)
生物活性 for GSK J5
Inactive isomer of GSK J4; also cell permeable ester derivative of the inactive control, GSK J2.
Active Analog also available.
许可信息
This compound is supplied in conjunction with the Structural Genomics Consortium. For further characterization details of GSK J5, a cell permeable inactive isomer of GSK J1, please visit the GSK J1 probe summary on the SGC website.
技术数据 for GSK J5
| 分子量 | 417.5 |
| 公式 | C24H27N5O2 |
| 储存 | Store at RT |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 1394854-51-3 |
| PubChem ID | 78243729 |
| InChI Key | LQPGVGSKBNXQDU-UHFFFAOYSA-N |
| Smiles | O=C(CCNC1=NC(C2=CC=CN=C2)=NC(N3CCC(C=CC=C4)=C4CC3)=C1)OCC |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for GSK J5
参考文献 for GSK J5
参考文献是支持产品生物活性的出版物。
Kruidenier et al (2012) A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature 488 404 PMID: 22842901
按产品操作查看相关产品
关键词: GSK J5, GSK J5 supplier, GSKJ5, histone, demethylases, inhibitors, inhibits, UTX, JMJD3, KDM6, H3K27, epigenetics, Histone, Demethylases, 4689, Tocris Bioscience
2 篇 GSK J5 的引用文献
引用文献是使用了 Tocris 产品的出版物。 GSK J5 的部分引用包括：
Bayo et al (2018) Jumonji Inhibitors Overcome Radioresistance in Cancer through Changes in H3K4 Methylation at Double-Strand Breaks. Cell Rep 25 1040 PMID: 30355483
Carey et al (2015) Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells. Int J Nanomedicine 518 413 PMID: 25487152
GSK J5 的评论
目前没有该产品的评论。 Be the first to review GSK J5 and earn rewards!
Have you used GSK J5?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Epigenetics Scientific Review
Written by Susanne Müller-Knapp and Peter J. Brown, this review gives an overview of the development of chemical probes for epigenetic targets, as well as the impact of these tool compounds being made available to the scientific community. In addition, their biological effects are also discussed. Epigenetic compounds available from Tocris are listed.