主页 / 药理学 / Ion Channels / Potassium Channels / Calcium-Activated Potassium (KCa) Channels / Calcium-Activated Potassium (KCa) Channel Activators / GW 542573X

GW 542573X

Cat. No. 4311 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Selective KCa2.1 (SK) channel activator
化学名： 4-[[[[(2-Methoxyphenyl)amino]carbonyl]oxy]methyl]-piperidinecarboxylic acid-1,1-dimethylethyl ester
纯度： ≥99% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for GW 542573X

GW 542573X is an activator of small-conductance Ca2+-activated K+ channels (KCa2); selective for KCa2.1 (EC50 = 8.2 μM in HEK293 cells expressing hKCa2.1) with the profile hKCa2.1 > hKCa2.2 = hKCa2.3 > hKCa3.1 (IK).

化合物库 for GW 542573X

GW 542573X is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for GW 542573X

分子量 364.44
公式 C19H28N2O5
储存 Store at +4°C
纯度 ≥99% (HPLC)
CAS Number 660846-41-3
PubChem ID 24885053
InChI Key SAXGSDIZIYFNKD-UHFFFAOYSA-N
Smiles O=C(OC(C)(C)C)N1CCC(COC(NC2=CC=CC=C2OC)=O)CC1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for GW 542573X

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 36.44 100
ethanol 36.44 100

制备储备液 for GW 542573X

以下数据基于产品分子量 364.44。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.74 mL 13.72 mL 27.44 mL
5 mM 0.55 mL 2.74 mL 5.49 mL
10 mM 0.27 mL 1.37 mL 2.74 mL
50 mM 0.05 mL 0.27 mL 0.55 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

参考文献 for GW 542573X

参考文献是支持产品生物活性的出版物。

Hougaard et al (2009) Selective activation of the SK1 subtype of human small-conductance Ca2+-activated K+ channels by 4-(2-methyoxy-phenylcarbamoyloxymethyl)-piperidine-1-carboxylic acid tert-butyl ester (GW542573X) is dependent on serine 298 in Mol.Pharmacol. 76 569 PMID: 19515965

If you know of a relevant reference for GW 542573X, please let us know.

按标靶查看相关产品

按产品操作查看相关产品

查看全部 Calcium-Activated Potassium (KCa) Channel Activators

关键词: GW 542573X, GW 542573X supplier, GW542573X, potassium, channels, activators, KCa2, KCa2.1, KCa2.2, KCa2.3, SK, SK1, activates, calcium-activated, Ca2+-Activated, Potassium, Channels, 4311, Tocris Bioscience

篇 GW 542573X 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 GW 542573X 的引用文献。 您是否知道使用了 Tocris GW 542573X 的优秀论文？ 请告知我们.

GW 542573X 的评论

目前没有该产品的评论。 Be the first to review GW 542573X and earn rewards!

Have you used GW 542573X?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review