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Submit ReviewHemokinin 1 (mouse)
说明： Endogenous, high affinity and selective NK1 agonist
别名： HK-1,HEK-1
生物活性 for Hemokinin 1 (mouse)
Novel mammalian endogenous peptide, homolog of substance P, that is a high affinity and selective agonist at the tachykinin NK1 receptor (Ki values are 0.175 and 560 nM for NK1 and NK2 receptors respectively). Has proliferative and antiapoptotic actions on B-cells in vitro and is antihypertensive in vivo.
技术数据 for Hemokinin 1 (mouse)
| 分子量 | 1413.66 |
| 公式 | C61H100N22O15S |
| 序列 |
RSRTRQFYGLM (Modifications: Met-11 = C-terminal amide) |
| 储存 | Store at -20°C |
| CAS Number | 208041-90-1 |
| PubChem ID | 90479800 |
| InChI Key | ZOLDEMZLDJFVRY-RULPZMNSSA-N |
| Smiles | [H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Hemokinin 1 (mouse)
参考文献 for Hemokinin 1 (mouse)
参考文献是支持产品生物活性的出版物。
Bellucci et al (2002) Pharmacological profile of the novel mammalian tachykinin hemokinin 1. Br.J.Pharmacol. 135 266 PMID: 11786503
Morteau et al (2001) Hemokinin 1 is a full agonist at the substance P receptor. Nat.Immunol. 2 1088 PMID: 11725292
Zhang et al (2000) Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis. Nat.Immunol. 1 392 PMID: 11062498
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关键词: Hemokinin 1 (mouse), Hemokinin 1 (mouse) supplier, Endogenous, high, affinity, selective, NK1, agonists, Tachykinin, Receptors, Neurokinin, Hemokinin1, (mouse), HK-1, HEK-1, Receptor, 1535, Tocris Bioscience
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