Hemopressin (human, mouse)

Name: Hemopressin (human, mouse)
Brand: Tocris Bioscience
SKU: 3791
Rating: 5 (1 reviews)

Cat. No. 3791 1 次引用 1 条评论提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Selective CB₁ inverse agonist

说明书

引用文献 (1)

文献 (2)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Hemopressin (human, mouse)

Hemopressin (human, mouse) is a bioactive endogenous peptide substrate for endopeptidase 24.15 (ep24.15), neurolysin (ep24.16) and ACE. K_i values are 27.76, 3.43 and 1.87 μM respectively. Potent hypotensive in vivo. Also acts as a selective CB₁ receptor inverse agonist. Displays antinociceptive activity in vivo.

技术数据 for Hemopressin (human, mouse)

分子量	1054.26
公式	C₅₀H₇₉N₁₃O₁₂
序列	PVNFKLLSH
储存	Store at -20°C
CAS Number	1314035-51-2
PubChem ID	90488877
InChI Key	JEXQOFXDPAGOQL-TZFLQVIRSA-N
Smiles	[H]N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC=N1)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Hemopressin (human, mouse)

溶解性	Soluble to 1 mg/ml in water

产品说明书 for Hemopressin (human, mouse)

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Hemopressin (human, mouse)

参考文献是支持产品生物活性的出版物。

Rioli et al (2003) Novel natural peptide substrates for endopeptidase 24.15, neurolysin, and angiotensin-converting enzyme. J.Biol.Chem. 278 8547 PMID: 12500972

Blais et al (2005) Hypotensive effects of hemopressin and bradykinin in rabbits, rats and mice. A comparative study. Peptides 26 1317 PMID: 16042973

Heimann et al (2007) Hemopressin is an inverse agonist of CB₁ cannabinoid receptors. Proc.Natl.Acad.Sci.USA 104 20588

If you know of a relevant reference for Hemopressin (human, mouse), please let us know.

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关键词: Hemopressin (human, mouse), Hemopressin (human, mouse) supplier, Bioactive, endopeptidase, 2415, neurolysin, ACE, Angiotensin-Converting, Enzyme, Proteinases, Proteases, Substrates, activators, cannabinoids, receptors, CB1, inverse, agonists, antagonists, cb1r, Receptors, Other, /, Activators, 3791, Tocris Bioscience

1 篇 Hemopressin (human, mouse) 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Hemopressin (human, mouse) 的部分引用包括：

Jimenez-Blasco et al (2020) Glucose metabolism links astroglial mitochondria to cannabinoid effects. Nature 583 603 PMID: 32641832

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Hemopressin (human, mouse) 的评论

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Our experiments looked into CB1 receptors using Hemopressin.

By Anonymous on 02/19/2019

种属： Human

The endocannabinoid system consists of at least two cannabinoid receptors, CB1 and CB2. Our experiments looked into CB1 receptors using Hemopressin and they were cloned.

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