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Submit ReviewHeparin sodium salt is a minimum activity: > 150 I.U./mg. Glycosaminoglycan that behaves as an anticoagulant. Binds with high affinity to antithrombin III (AT-III). Used in protocols to generate kidney or brain organoids from human pluripotent stem cells.
For more information about how Heparin sodium salt may be used, see our protocol: Generation of Kidney Organoids from hPSCs
储存 | Desiccate at RT |
CAS Number | 9041-08-1 |
PubChem ID | 25244225 |
InChI Key | OHJKXVLJWUPWQG-IUYNYSEKSA-J |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性 | Soluble to 50 mg/ml in water |
参考文献是支持产品生物活性的出版物。
Lever and Page (2002) Novel drug development opportunities for he. Nat.Rev.Drug Discov. 1 140 PMID: 12120095
Takasato et al (2016) Generation of kidney organoids from human pluripotent stem cells. Nat.Protoc. 11 1681 PMID: 1681
Schafer (2023) An in vivo neuroimmune organoid model to study human microglia phenotypes. Cell 186 1222 PMID: 37172564
If you know of a relevant reference for Heparin sodium salt, please let us know.
关键词: Heparin sodium salt, Heparin sodium salt supplier, Anticoagulant, heparin, Adhesion, Molecules, antithrombin, III, organoids, Cell, Organoids, 2812, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 Heparin sodium salt 的部分引用包括:
Zhou et al (2019) Angiopoietin-2 induces the neuronal differentiation of mouse embryonic NSCs via phosphatidylinositol 3 kinase-Akt pathway-mediated phosphorylation of mTOR. Am J Transl Res 11 1895 PMID: 30972213
Bousquenaud et al (2012) Monocyte chemotactic protein 3 is a homing factor for circulating angiogenic cells. Hum Mol Genet 94 519 PMID: 22492674
Bakri et al (2016) Embryo apoptosis identification: Oocyte grade or cleavage stage? Saudi J Biol Sci 23 S50 PMID: 26858565
Schafer et al (2023) An in vivo neuroimmune organoid model to study human microglia phenotypes. Cell 186 2111 PMID: 37172564
Srinivasan et al (2018) Androgen receptor expression reduces stemness characteristics of prostate cancer cells (PC3) by repression of CD44 and SOX2. J Cell Biochem PMID: 30206982
You et al (2015) Impact of Nanotopography, he. Hydrogel Microstructures, and Encapsulated Fibroblasts on Phenotype of Primary Hepatocytes. ACS Appl Mater Interfaces 7 12299 PMID: 25247391
Battefeld et al (2019) High-Frequency Microdomain Ca2+ Transients and Waves during Early Myelin Internode Remodeling. Cell Rep 26 182 PMID: 30605675
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平均评分: 5 (Based on 1 Review.)
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We used Heparin sodium salt to stimulate proliferation of primary epithelial cells.Heparin solutions were sterilized by filtering through a sterilemembrane filter with a porosity of 0.22micron or less.
Do not autoclave heparin solutions