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Hexa-D-arginine

Cat. No. 4711 2 篇引用文献 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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4711 has been discontinued.

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说明： Furin inhibitor
纯度： ≥95% (HPLC)
说明书
引用文献 (2)
评论
生物活性 技术数据 说明书 参考文献

生物活性 for Hexa-D-arginine

Hexa-D-arginine is an inhibitor of furin (Ki values are 0.106, 0.58 and 13.2 μM for furin, PACE4 and PC1 respectively).

技术数据 for Hexa-D-arginine

分子量 954.16
公式 C36H75N25O6
序列 RRRRRR

(Modifications: Arg-6 = C-terminal amide, Arg-1,2,3,4,5,6 = D-Arg)
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 673202-67-0
PubChem ID 57358476
InChI Key BMLTZEAFQLJTIZ-TZNXUKFXSA-N
Smiles [H]N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(N)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Hexa-D-arginine

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for Hexa-D-arginine

参考文献是支持产品生物活性的出版物。

Yuan et al (2012) Hexa-D-arginine treatment increases 7B2.PC2 activity in hyp-mouse osteoblasts and rescues the HYP phenotype. J.Bone Miner.Res. 28 56 PMID: 22886699

Cameron et al (2000) Polyarginines are potent furin inhibitors. J.Biol.Chem. 275 36741 PMID: 10958789

Cheng et al (2020) Furin inhibitors block SARS-CoV-2 spike protein cleavage to suppress virus production and cytopathic effects. Cell Rep. 33 PMID: 33007239

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关键词: Hexa-D-arginine, Hexa-D-arginine supplier, Hexa-D-arginine, selective, furin, inhibitors, inhibits, paired, basic, amino, acid, cleaving, enzyme, PACE, subtilisin-like, proprotein, convertases, Furin, 4711, Tocris Bioscience

2 篇 Hexa-D-arginine 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Hexa-D-arginine 的部分引用包括：

Cheng et al (2020) Furin inhibitors block SARS-CoV-2 spike protein cleavage to suppress virus production and cytopathic effects. Cell Rep. PMID: 33007239

Wang et al (2019) Biowire Model of Interstitial and Focal Cardiac Fibrosis. ACS Cent Sci 5 1146 PMID: 31403068

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