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Submit ReviewHFI 142
说明： Insulin-regulated aminopeptidase (IRAP) inhibitor
化学名： Ethyl 2-amino-7-hydroxy-4-(3-pyridinyl)-4H-1-benzopyran-3-carboxylate
纯度： ≥98% (HPLC)
生物活性 for HFI 142
Insulin-regulated aminopeptidase (IRAP) inhibitor (Ki = 2.01 μM). Improves memory in control and memory-deficient mice models.
技术数据 for HFI 142
| 分子量 | 312.32 |
| 公式 | C17H16N2O4 |
| 储存 | Store at -20°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 332164-34-8 |
| PubChem ID | 655457 |
| InChI Key | JOPNHSIHFSZJMB-UHFFFAOYSA-N |
| Smiles | OC1=CC(OC(N)=C(C(OCC)=O)C2C3=CN=CC=C3)=C2C=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for HFI 142
参考文献 for HFI 142
参考文献是支持产品生物活性的出版物。
Albiston et al (2010) Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobic packing point at the active site of Ins-regulated aminopeptidase. Mol.Pharmacol. 78 600 PMID: 20628006
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关键词: HFI 142, HFI 142 supplier, HFI, 142, inhibitors, inhibits, insulin-regulated, aminopeptidases, IRAPs, memory, Aminopeptidases, 5627, Tocris Bioscience
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