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Submit ReviewIBC 293
Discontinued Product
2469 has been discontinued.
View all Hydroxycarboxylic Acid Receptors products.
说明： Selective agonist for the GPR109B (HM74) receptor. Antilipolytic
化学名： 1-(1-Methylethyl)-1H-benzotriazole-5-carboxylic acid
纯度： ≥99% (HPLC)
生物活性 for IBC 293
IBC 293 is a highly selective agonist for GPR109B (HM74), human orphan G-protein-coupled receptor expressed in adipocytes. Selective for GPR109B over niacin receptor GPR109A (HM74A); EC50 values are 400 nM and > 1 μM respectively. Inhibits isoproterenol-stimulated lipolysis in vitro in isolated human adipocytes.
技术数据 for IBC 293
| 分子量 | 205.22 |
| 公式 | C10H11N3O2 |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 306935-41-1 |
| PubChem ID | 2736690 |
| InChI Key | RUTVRAJKELSHCC-UHFFFAOYSA-N |
| Smiles | CC(C)N1N=NC2=CC(=CC=C12)C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for IBC 293
参考文献 for IBC 293
参考文献是支持产品生物活性的出版物。
Semple et al (2006) 1-Alkyl-benzotriazole-5-carboxylic acids are highly selective agonists of the human orphan G-protein-coupled receptor GPR109b. J.Med.Chem. 49 1227 PMID: 16480258
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关键词: IBC 293, IBC 293 supplier, Selective, agonists, GPR109B, HM74, receptors, Antilipolytic, GPR109, Receptors, Nicotinic, Acid, IBC293, Hydroxycarboxylic, 2469, Tocris Bioscience
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