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Submit ReviewIPG-4 AM
说明： Fluorescent potassium ion (K+) indicator, membrane permeable
化学名： Acetyloxymethyl 3-[3-(acetyloxymethoxy)-7-[3-(acetyloxymethoxy)-3-oxopropyl]-4,5-dichloro-9-[4-(5,17-dimethyl-8,14,24,27,32,35-hexaoxa-1,11,21-triazatetracyclo[19.8.8.02,7.015,20]heptatriaconta-2(7),3,5,15(20),16,18-hexaen-11-yl)-3-(2-methoxyethoxy)phenyl]-6-oxoxanthen-2-yl]propanoate
纯度： ≥90% (HPLC)
生物活性 for IPG-4 AM
IPG-4 AM is a membrane-permeable fluorescent potassium ion (K+) indicator. It binds to potassium (Kd = 7 mM). Excitation and emission maxima (λ) are 525 and 545 nm, respectively. It has 100:1 selectivity for K+ over Na+ ions. It can be used to detect in real time changes in intracellular K+. Also used to monitor extracellular K+ changes in vivo.
It is recommended to prepare stock solutions in DMSO.
Optical Data for IPG-4 AM
| λabs | 525 nm |
|---|---|
| λem | 545 nm |
| Cell Permeable | Yes |
| Application | Confocal microscopy, Flow cytometry |
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技术数据 for IPG-4 AM
| 分子量 | 1333.27 |
| 公式 | C67H79Cl2N3O21 |
| 储存 | Store at -20°C |
| 纯度 | ≥90% (HPLC) |
| CAS Number | 3019514-72-5 |
| PubChem ID | 163342041 |
| InChI Key | ORCBRKCLNTYBFH-UHFFFAOYSA-N |
| Smiles | O=C(C)OCOC(CCC1=CC2=C(C3=CC(OCCOC)=C(N(CCOC4=C5C=CC(C)=C4)CCOC6=C(N7CCOCCOCCN5CCOCCOCC7)C=CC(C)=C6)C=C3)C8=C(C(Cl)=C(C(CCC(OCOC(C)=O)=O)=C8)OCOC(C)=O)OC2=C(C1=O)Cl)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for IPG-4 AM
参考文献 for IPG-4 AM
参考文献是支持产品生物活性的出版物。
Rana et al (2019) Calibration and characterization of intracellular Asante Potassium Green probes, APG-2 and APG-4. Anal.Biochem. 567 8 PMID: 30503709
Kikuchi et al (2022) Electrochemical potential enables dormant spores to integrate environmental signals. Science 378 43 PMID: 36201591
Humphries et al (2017) Species-independent attraction to biofilms through electrical signaling. Cell 168 200 PMID: 28086091
Hanalioglu et al (2022) Cortical spreading depression can be triggered by sensory stimulation in primed wild type mouse brain: a mechanistic insight to migraine aura generation. J.Headache Pain 23 107 PMID: 35986251
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关键词: IPG-4 AM, IPG-4 AM supplier, IPG-4AM, membrane, permeable, fluorescent, probe, fluorescein, detection, fluorescence, indicators, sensors, potassium, ions, K, ion, intracellular, extracellular, in, vivo, Fluorescent, Ion, Indicators, 7871, Tocris Bioscience
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Fluorescent Dyes and Probes Research Product Guide
This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:
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- Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
- Tissue Clearing Kits and Reagents
- Aptamer-based RNA Imaging Reagents
- Fluorescent Probes for Imaging Bacteria
- TSA VividTM Fluorophore Kits
- TSA Reagents for Enhancing IHC, ICC & FISH Signals