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L 012 sodium salt

Cat. No. 5085 2 篇引用文献 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Chemiluminescent ROS and RNS indicator
化学名： 8-Amino-5-chloro-2,3-dihydro-7-phenyl-pyrido[3,4-d]pyridazine sodium salt
纯度： ≥98% (HPLC)
说明书
引用文献 (2)
评论
文献 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for L 012 sodium salt

L 012 sodium salt is a luminal-based chemiluminescent probe. Detects NAPDH oxidase-derived reactive oxygen and nitrogen species (ROS and RNS). Active in vitro and in vivo.

技术数据 for L 012 sodium salt

分子量 310.67
公式 C13H8CIN4NaO2
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 143556-24-5
PubChem ID 78243715
InChI Key IGEUYSJHQQCEFP-UHFFFAOYSA-M
Smiles NC1=C3C(C(O[Na])=NNC3=O)=C(Cl)N=C1C2=CC=CC=C2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for L 012 sodium salt

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 6.21 20
DMSO 31.07 100

制备储备液 for L 012 sodium salt

以下数据基于产品分子量 310.67。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 3.22 mL 16.09 mL 32.19 mL
5 mM 0.64 mL 3.22 mL 6.44 mL
10 mM 0.32 mL 1.61 mL 3.22 mL
50 mM 0.06 mL 0.32 mL 0.64 mL

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产品说明书 for L 012 sodium salt

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for L 012 sodium salt

参考文献是支持产品生物活性的出版物。

Kielland et al (2009) In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012. Free Radic.Biol.Med. 47 760 PMID: 19539751

Zhou et al (2012) Noninvasive assessment of localized inflammatory responses. Free Radic.Biol.Med. 52 218 PMID: 22080048

Ichibangase et al (2013) Evaluation of lophine derivatives as L-012 (luminol analog)-dependent chemiluminescence enhancers for measuring horseradish peroxidase and H2 O2. Luminescence. 29 118 PMID: 23630098

If you know of a relevant reference for L 012 sodium salt, please let us know.

按标靶查看相关产品

关键词: L 012 sodium salt, L 012 sodium salt supplier, L012, sodium, salt, chemiluminescent, reactive, oxygen, nitrogen, species, fluorescent, probes, Fluorescent, Cell, Indicators, and, Sensors, Other, Nitric, Oxide, 5085, Tocris Bioscience

2 篇 L 012 sodium salt 的引用文献

引用文献是使用了 Tocris 产品的出版物。 L 012 sodium salt 的部分引用包括：

Jie et al (2020) IL-33/ST2 induces neutrophil-dependent reactive oxygen species production and mediates gout pain. Theranostics 10 12189-12203 PMID: 33204337

Mentrup et al (2022) Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteolysis. Nat.Commun. 13 1880 PMID: 35388002

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Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

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