主页 / 细胞生物学 / Cell Metabolism / DNA, RNA and Protein Synthesis / Lac-Phe

Lac-Phe

Cat. No. 7942 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Metabolite generated by cytosol nonspecific dipeptidase (CNDP2) during intense exercise
化学名： N-[(2S)-2-Hydroxy-1-oxopropyl]-L-phenylalanine
纯度： ≥95% (HPLC)
说明书
引用文献
评论
文献 (2)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Lac-Phe

Lac-Phe is a metabolite generated from lactate and phenylalanine by cytosolic non-specific dipeptidase (CNDP2) during intense exercise. Lac-Phe reduces food intake in diet-induced obese mice without affecting movement or energy expenditure. When administrated chronically, Lac-Phe decreases adiposity and body weight and improves glucose homeostasis.

技术数据 for Lac-Phe

分子量 237.26
公式 C12H15NO4
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 183241-73-8
PubChem ID 11075454
InChI Key IIRJJZHHNGABMQ-WPRPVWTQSA-N
Smiles C[C@H](O)C(N[C@H](C(O)=O)CC1=CC=CC=C1)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Lac-Phe

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 23.73 100

制备储备液 for Lac-Phe

以下数据基于产品分子量 237.26。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 4.21 mL 21.07 mL 42.15 mL
5 mM 0.84 mL 4.21 mL 8.43 mL
10 mM 0.42 mL 2.11 mL 4.21 mL
50 mM 0.08 mL 0.42 mL 0.84 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

参考文献 for Lac-Phe

参考文献是支持产品生物活性的出版物。

Li et al (2022) An exercise-inducible metabolite that suppresses feeding and obesity. Nature 606 785 PMID: 35705806

If you know of a relevant reference for Lac-Phe, please let us know.

按标靶查看相关产品

关键词: Lac-Phe, Lac-Phe supplier, Obesity, adipose, tissue, L-lactate-derived, DIO, lactoyl, phenylalanine, exercises, appetite, amino, acids, reverse, proteolysis, DNA,, RNA, and, Protein, Synthesis, 7942, Tocris Bioscience

篇 Lac-Phe 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 Lac-Phe 的引用文献。 您是否知道使用了 Tocris Lac-Phe 的优秀论文？ 请告知我们.

Lac-Phe 的评论

目前没有该产品的评论。 Be the first to review Lac-Phe and earn rewards!

Have you used Lac-Phe?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Cell Cycle and DNA Damage Research Product Guide

Cell Cycle and DNA Damage Research Product Guide

This product guide provides a review of the cell cycle and DNA damage research area and lists over 150 products, including research tools for:

  • Cell Cycle and Mitosis
  • DNA Damage Repair
  • Targeted Protein Degradation
  • Ubiquitin Proteasome Pathway
  • Chemotherapy Targets
Huntington's Disease Research Product Guide

Huntington's Disease Research Product Guide

This product guide provides a background to Huntington's disease research and lists around 100 products for the study of:

  • Somatic Instability
  • Proteolysis and Inclusion Bodies
  • Transcriptional Dysregulation
  • Mitochondrial Dysfunction
  • Nuclear-Cytoplasmic Transport Interference
  • Excitotoxicity
  • Stem Cells