主页 / Product Type / 荧光成像 / Fluorescent Probes and Stains / Fluorescent Lipid Probes and Cell Membrane Stains / Laurdan

Laurdan

Cat. No. 7275 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Polarity sensitive lipid membrane fluorescent probe. Used for: imaging lipid rafts. Application: fluorescent microscopy
化学名： 1-[6-(Dimethylamino)-2-naphthalenyl]-1-dodecanone
纯度： ≥95% (HPLC)
说明书
引用文献
评论
文献 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Laurdan

Key information: Laurdan is a polarity sensitive fluorescent probe for imaging lipid rafts in membranes (also known as lipid microdomains). Suitable for live and fixed cells as well as in whole tissues imaging with multiphoton microscopy.

Used for: imaging lipid raft and cell membrane investigations.

Application: fluorescence microscope. Suitable for use with generalized polarization (GP) imaging and scanning fluorescence correlation spectroscopy (FCS).

Properties and Photophysical Data: When Laurdan is incorporated into membranes, its fluorescence spectra is sensitive to the physical state of the surrounding phospholipids. Excitation and emission maxima (λ) are 366 nm and 497 nm, respectively; quantum yield = 0.61; extinction coefficient = 19,500 M-1cm-1. In gel and liquid phase membranes, excitation and emission maxima (λ) are 440 nm and 490 nm, respectively.

Optical Data for Laurdan

Laurdan Dye Spectra
Emission Color Blue
λabs 366 nm
λem 497 nm
Extinction Coefficient (ε) 19500 M-1cm-1
Quantum Yield (φ) 0.61
Application Polarity Sensitive Fluorescent Probe for Lipid Raft and Cell Membrane Investigations
Alternative For C-Laurdan, Di-4-ANEPPDHQ

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectral Viewer

Spectral Viewer

技术数据 for Laurdan

分子量 353.55
公式 C24H35NO
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 74515-25-6
PubChem ID 104983
InChI Key JHDGGIDITFLRJY-UHFFFAOYSA-N
Smiles CCCCCCCCCCCC(C1=CC2=CC=C(N(C)C)C=C2C=C1)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Laurdan

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMF 7.07 20

制备储备液 for Laurdan

以下数据基于产品分子量 353.55。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.2 mM 14.14 mL 70.71 mL 141.42 mL
1 mM 2.83 mL 14.14 mL 28.28 mL
2 mM 1.41 mL 7.07 mL 14.14 mL
10 mM 0.28 mL 1.41 mL 2.83 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

参考文献 for Laurdan

参考文献是支持产品生物活性的出版物。

Sanchez et al (2012) Laurdan generalized polarization fluctuations measures membrane packing micro-heterogeneity in vivo. Proc.Natl.Acad.Sci.U.S.A. 109 7314 PMID: 22529342

Owen et al (2011) Quantitative imaging of membrane lipid order in cells and organisms. Nat.Protoc. 7 24 PMID: 22157973

If you know of a relevant reference for Laurdan, please let us know.

按标靶查看相关产品

关键词: Laurdan, Laurdan supplier, fluorescent, probe, imaging, lipid, rafts, membrane, polarity, multiphoton, microscopy, generalized, polarization, GP, and, scanning, fluorescence, correlation, spectroscopy, FCS, Fluorescent, Lipid, Probes, Cell, Membrane, Stains, 7275, Tocris Bioscience

篇 Laurdan 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 Laurdan 的引用文献。 您是否知道使用了 Tocris Laurdan 的优秀论文？ 请告知我们.

Laurdan 的评论

目前没有该产品的评论。 Be the first to review Laurdan and earn rewards!

Have you used Laurdan?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:

  • Fluorescent Dyes, including dyes for flow cytometry
  • Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
  • Tissue Clearing Kits and Reagents
  • Aptamer-based RNA Imaging Reagents
  • Fluorescent Probes for Imaging Bacteria
  • TSA VividTM Fluorophore Kits
  • TSA Reagents for Enhancing IHC, ICC & FISH Signals