主页 / Product Type / PROTAC® Degraders & Targeted Protein Degradation / Degrader Building Blocks / Cereblon Targeting Ligands Plus Linkers / Lenalidomide 4'-PEG3-azide

Lenalidomide 4'-PEG3-azide

Cat. No. 7515 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

7515 has been discontinued.

View all Cereblon Targeting Ligands Plus Linkers products.
说明： Cereblon ligand with PEG linker and terminal azide for onward chemistry
化学名： 3-[4-[[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl]amino]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione
纯度： ≥95% (HPLC)
说明书
引用文献
评论
文献 (2)
生物活性 技术数据 说明书 参考文献

生物活性 for Lenalidomide 4'-PEG3-azide

Lenalidomide 4'-PEG3-azide is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG3 linker with terminal azide ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines for Lenalidomide 4'-PEG3-azide

This product is provided for use in onward chemistry. Suitable solvents can be used.

技术数据 for Lenalidomide 4'-PEG3-azide

分子量 460.49
公式 C21H28N6O6
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 2399455-51-5
PubChem ID 153375809
InChI Key VTBUBJKNPABXBX-UHFFFAOYSA-N
Smiles [N-]=[N+]=NCCOCCOCCOCCNC1=C2CN(C(C2=CC=C1)=O)C3CCC(NC3=O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Lenalidomide 4'-PEG3-azide

分析证书/产品说明书
化学品安全技术说明书

参考文献 for Lenalidomide 4'-PEG3-azide

参考文献是支持产品生物活性的出版物。

按标靶查看相关产品

关键词: Lenalidomide 4'-PEG3-azide, Lenalidomide 4'-PEG3-azide supplier, PROTAC, degraders, cereblon, E3, ubiquitin, ligase, PEG2, linker, conjugate, polyethylene, glycol, terminal, amine, building, blocks, components, targeted, protein, degradation, TPD, Cereblon, Ligands, Plus, Linkers, 7515, Tocris Bioscience

篇 Lenalidomide 4'-PEG3-azide 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 Lenalidomide 4'-PEG3-azide 的引用文献。

Lenalidomide 4'-PEG3-azide 的评论

目前没有该产品的评论。 Be the first to review Lenalidomide 4'-PEG3-azide and earn rewards!

Have you used Lenalidomide 4'-PEG3-azide?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

TPD and Induced Proximity Research Product Guide

TPD and Induced Proximity Research Product Guide

This brochure highlights the tools and services available from Bio-Techne to support your Targeted Protein Degradation and Induced Proximity research, including:

  • Active Degraders
  • TAG Degradation Platform
  • Degrader Building Blocks
  • Assays for Protein Degradation
  • Induced Proximity Tools
Targeted Protein Degradation Poster

Targeted Protein Degradation Poster

Degraders (e.g. PROTACs) are bifunctional small molecules, that harness the Ubiquitin Proteasome System (UPS) to selectively degrade target proteins within cells. They consist of three covalently linked components: an E3 ubiquitin ligase ligand, a linker and a ligand for the target protein of interest. Authored in-house, this poster outlines the generation of a toolbox of building blocks for the development of Degraders. The characteristics and selection of each of these components are discussed. Presented at EFMC 2018, Ljubljana, Slovenia